Enteric glial biology, intercellular signalling and roles in gastrointestinal disease
L Seguella, BD Gulbransen - Nature reviews Gastroenterology & …, 2021 - nature.com
One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …
many functions normally attributed to enteric neurons involve interactions with enteric glial …
The enteric nervous system in gastrointestinal disease etiology
AM Holland, AC Bon-Frauches, D Keszthelyi… - Cellular and Molecular …, 2021 - Springer
A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
Chemotherapy induced gastrointestinal toxicities
HI Akbarali, KH Muchhala, DK Jessup… - Advances in cancer …, 2022 - Elsevier
Chemotherapy—induced gastrointestinal dysfunction is a common occurrence associated
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …
Toll-like receptor 4–mediated enteric glia loss is critical for the development of necrotizing enterocolitis
ML Kovler, AJ Gonzalez Salazar, WB Fulton… - Science translational …, 2021 - science.org
Necrotizing enterocolitis (NEC) is a devastating disease of premature infants, whose
pathogenesis remains incompletely understood, although activation of the Gram-negative …
pathogenesis remains incompletely understood, although activation of the Gram-negative …
The S100B protein: A multifaceted pathogenic factor more than a biomarker
F Michetti, ME Clementi, R Di Liddo, F Valeriani… - International Journal of …, 2023 - mdpi.com
S100B is a calcium-binding protein mainly concentrated in astrocytes in the nervous system.
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …
S100 family proteins in inflammation and beyond
The S100 family proteins possess a variety of intracellular and extracellular functions. They
interact with multiple receptors and signal transducers to regulate pathways that govern …
interact with multiple receptors and signal transducers to regulate pathways that govern …
[HTML][HTML] Berberine regulates fecal metabolites to ameliorate 5-fluorouracil induced intestinal mucositis through modulating gut microbiota
H Chen, F Zhang, R Li, Y Liu, X Wang, X Zhang… - Biomedicine & …, 2020 - Elsevier
Berberine (BBR) is an isoquinoline alkaloid, which has been used in the treatment of
intestinal mucositis. However, BBR on chemotherapy-induced mucositis in cancer patients …
intestinal mucositis. However, BBR on chemotherapy-induced mucositis in cancer patients …
IL-1-dependent enteric gliosis guides intestinal inflammation and dysmotility and modulates macrophage function
R Schneider, P Leven, S Mallesh, M Breßer… - Communications …, 2022 - nature.com
Abstract Muscularis Externa Macrophages (ME-Macs) and enteric glial cells (EGCs) are
closely associated cell types in the bowel wall, and important interactions are thought to …
closely associated cell types in the bowel wall, and important interactions are thought to …
Atorvastatin calcium alleviates 5-fluorouracil-induced intestinal damage by inhibiting cellular senescence and significantly enhances its antitumor efficacy
J Xia, S He, Q Dai, H Jia, Y Ge, M Zhou… - International …, 2023 - Elsevier
Fluorouracil (5-Fu) is the preferred drug in colorectal cancer treatment. Although 5-Fu
treatment contributes to the increase in survival rates, long-term use of 5-Fu causes severe …
treatment contributes to the increase in survival rates, long-term use of 5-Fu causes severe …
The role of S100B/RAGE-enhanced ADAM17 activation in endothelial glycocalyx shedding after traumatic brain injury
Z Zou, L Li, Q Li, P Zhao, K Zhang, C Liu, D Cai… - Journal of …, 2022 - Springer
Background Traumatic brain injury (TBI) remains one of the main causes for disability and
death worldwide. While the primary mechanical injury cannot be avoided, the prevention of …
death worldwide. While the primary mechanical injury cannot be avoided, the prevention of …