Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Circadian rhythms are physiological and behavioural cycles generated by an endogenous
biological clock, the suprachiasmatic nucleus. The circadian system influences the majority …

Neurodegenerative diseases encompass a large group of conditions that are clinically and
pathologically diverse yet are linked by a shared pathology of misfolded proteins. The …

Obesity and consumption of a high-fat diet are known to increase the risk of Alzheimer's
disease (AD). Diets high in fat also increase disease neuropathology and/or cognitive …

Alzheimer's disease (AD) is increasingly recognized as a complex neurodegenerative
disease beginning decades prior to the cognitive decline. While cognitive deficits remain the …

Alzheimer's disease (AD) is a devastating neurodegenerative condition associated with
severe cognitive and behavioral impairments. Circadian rhythms are recurring cycles that …

Various forms of exercise have been shown to prevent, restore, or ameliorate a variety of
brain disorders including dementias, Parkinson's disease, chronic stress, thyroid disorders …

The impact of COVID-19 on the elderly is devastating, and nursing homes are struggling to
provide the best care to the most fragile. The urgency and severity of the pandemic forces …

The irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder
world wide that lasts for decades. The human gut harbors a diverse population of microbial …

Aging is by far the most prominent risk factor for Alzheimer's disease (AD), and both aging
and AD are associated with apparent metabolic alterations. As developing effective …