Aluminum neurotoxicity and autophagy: a mechanistic view

S Makhdoomi, S Ariafar, F Mirzaei… - Neurological …, 2023 - Taylor & Francis
It is strongly believed that aluminum is one of the insalubrious agents because of its
neurotoxicity effects and influences on amyloid β (Aβ) production and tau protein …

New insights in animal models of neurotoxicity-induced neurodegeneration

C Sanfeliu, C Bartra, C Suñol… - Frontiers in …, 2024 - frontiersin.org
The high prevalence of neurodegenerative diseases is an unintended consequence of the
high longevity of the population, together with the lack of effective preventive and therapeutic …

Antioxidant dihydrolipolic acid protects against in vitro aluminum‐induced toxicity

S Sanajou, A Yirün, G Demirel, DA Çakir… - Journal of Applied …, 2023 - Wiley Online Library
Dihydrolipoic acid (DHLA) is a natural antioxidant known for its ability to counteract metal
toxicity and oxidative stress. It has shown the potential to safeguard cells from harmful …

Evaluation of possible neuroprotective effects of virgin coconut oil on aluminum‐induced neurotoxicity in an in vitro Alzheimer's disease model

G Demirel, S Sanajou, A Yirün, DA Çakir… - Journal of Applied …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurological disorder that affects various
cognitive functions, behavior, and personality. AD is thought to be caused by a combination …

Walnut oil: a promising nutraceutical in reducing oxidative stress and improving cholinergic activity in an in vitro Alzheimer's disease model

G Demirel, S Sanajou, A Yirün, DA Çakır… - Toxicology …, 2024 - academic.oup.com
Improving the quality of life in elderly patients and finding new treatment options for
neurological diseases such as Alzheimer's has become one of the priorities in the scientific …

Heavy metals exposure and Alzheimer's disease: Underlying mechanisms and advancing therapeutic approaches

NA Althobaiti - Behavioural Brain Research, 2024 - Elsevier
Heavy metals such as lead, cadmium, mercury, and arsenic are prevalent in the
environment due to both natural and anthropogenic sources, leading to significant public …

Toxic Effects of Industrial Flocculants Addition on Bioconversion of Black Soldier Fly Larvae (Hermetia illucens L.)

Z Zhang, L Chen, K Yang, T Wang, Y Wang, Y Jia… - Insects, 2022 - mdpi.com
Simple Summary The black soldier fly (BSF) is a saprophagous insect that has been applied
to organic waste management while providing high-quality insect protein. Flocculants are …

Moringa oleifera leaves ethanolic extract counteracts cortical neurodegeneration induced by aluminum chloride in rats

RF Hindawy, SM Manawy, OE Nafea… - Toxicology …, 2024 - academic.oup.com
Background Aluminum, a well-recognized neurotoxin, is implicated in various
neurodegenerative disorders. Moringa oleifera (M. oleifera), known as a miracle tree, is …

The ameliorative potential of metformin against aluminum‐induced neurotoxicity: Insights from in vitro studies

S Sanajou, A Yirün, G Demirel… - Journal of Applied …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is increasingly recognized as a metabolic disorder, often referred
to as type 3 diabetes, due to its strong association with insulin resistance. Chronic exposure …

Unraveling the neuroprotective mechanisms of naltrexone against aluminum-induced neurotoxicity

S Sanajou, A Yirün, D Arca Çakır… - Drug and chemical …, 2024 - Taylor & Francis
Aluminum (Al) is a known neurotoxic trace element linked to Alzheimer's disease (AD).
Naltrexone, an opioid antagonist, has shown promising effects in reducing …