In situ forming implants (ISI) based on phase separation by solvent exchange represent an
attractive alternative to conventional preformed implants and microparticles for parenteral …

Aporous [3-tricalcium phosphate material for bone implan tation is provided. The multiple
pores in the porous TCP body are separate discrete voids and are not interconnected. The …

The research of radiation effects on drugs over the past 60 years has mainly dealt with
radiation sterilization of individual active pharmaceutical ingredients (APIs) in the form of …

Many craniofacial birth defects contain skeletal components requiring bone grafting. We
previously identified the novel secreted osteogenic molecule NELL-1, first noted to be …

Background: Bone morphogenetic proteins (BMPs) are being evaluated as candidates for
periodontal and bone regenerative therapy. However, the research on recombinant human …

Maxillary bone deficiencies, such as cleft palate and underdeveloped maxilla that require
bone graft or regeneration after orthopedic or surgical expansion, pose a significant …

We previously identified osteoactivin (OA) as a novel secreted osteogenic factor with high
expression in developing long bones and calvaria, and that stimulates osteoblast …

US7390498B2 - Method of forming bone with porous βtricalcium phosphate granules -
Google Patents US7390498B2 - Method of forming bone with porous βtricalcium phosphate …

Background: The cholesterol‐lowering drug simvastatin promotes bone formation in cell
cultures and animal models. In previous studies, devices for the controlled, localized …

Background. The effectiveness of chemotherapeutic agents is proportional to the dose of the
agents at their targets; however, the dose is limited by systemic toxicity. Attempts have been …