Histology permits the observation of otherwise invisible structures of the internal topography
of a specimen. Although it enables the investigation of tissues at a cellular level, it is invasive …

Automated microscopy can image specimens larger than the microscope's field of view
(FOV) by stitching overlapping image tiles. It also enables time-lapse studies of entire cell …

Background The goal of this survey paper is to overview cellular measurements using
optical microscopy imaging followed by automated image segmentation. The cellular …

Current biomedical research increasingly requires imaging large and thick 3D structures at
high resolution. Prominent examples are the tracking of fine filaments over long distances in …

The term vasculogenic mimicry (VM) refers to the capacity of certain cancer cells to form fluid-
conducting structures within a tumor in an endothelial cell (EC)-free manner. Ever since its …

The field of connectomics aims to reconstruct the wiring diagram of Neurons and synapses
to enable new insights into the workings of the brain. Reconstructing and analyzing the …

Fluorescent nanodiamonds (FND) as specifically targeted probes to image the interactions
of transferrins (Tf) with their receptors that were over-expressed on HeLa cells were studied …

After oncogenic transformation, tumor cells rewire their metabolism to obtain sufficient
energy and biochemical building blocks for cell proliferation, even under hypoxic conditions …

There is a necessity to better characterize uveal melanoma (UM) tumors according to their
metastasis potential at an early stage. In this study we report the identification of potential …

We introduce NeuroConstruct, a novel end-to-end application for the segmentation,
registration, and visualization of brain volumes imaged using wide-field microscopy …