Axons in the peripheral nervous system have the ability to repair themselves after damage,
whereas axons in the central nervous system are unable to do so. A common and important …

Metabolic reprogramming is of great significance in the progression of various cancers and
is critical for cancer progression, diagnosis, and treatment. Cellular metabolic pathways …

Lysophosphatidic acid (LPA) species accumulate in the ascites of ovarian high-grade
serous cancer (HGSC) and are associated with short relapse-free survival. LPA is known to …

The endoplasmic reticulum (ER) is responsible for structural transformation or folding of de
novo proteins for transport to the Golgi. When the folding capacity of the ER is exceeded or …

Hepatocellular carcinoma (HCC) is the fifth most common neoplasm and a major cause of
cancer-related death worldwide. There is no ideal biomarker allowing early diagnosis of …

Childhood cancer is considered rare, corresponding to~ 3% of all malignant neoplasms in
the human population. The World Health Organization (WHO) reports a universal …

Currently, corneal blindness is affecting> 10 million individuals worldwide, and there is a
significant unmet medical need because only 1.5% of transplantation needs are met globally …

Esophageal squamous cell carcinoma (ESCC) is an upper gastrointestinal cancer with high
morbidity and mortality. New strategies are urgently needed to prolong patients' survival …

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with high mortality
that urgently requires new treatments. ROCK1 plays an essential role in regulating growth …

In osteosarcoma patients, metastasis of the primary cancer is the leading cause of death. At
present, management options to prevent metastasis are limited and non-curative. In this …