Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

A large population of neural stem/precursor cells (NSCs) persists in the ventricular–
subventricular zone (V-SVZ) located in the walls of the lateral brain ventricles. V-SVZ NSCs …

Various chronic antidepressant treatments increase adult hippocampal neurogenesis, but
the functional importance of this phenomenon remains unclear. Here, using genetic and …

Neural stem cells exist not only in the developing mammalian nervous system but also in the
adult nervous system of all mammalian organisms, including humans. Neural stem cells can …

Neural stem cells reside in the subventricular zone (SVZ) of the adult mammalian brain. This
germinal region, which continually generates new neurons destined for the olfactory bulb, is …

Multipotent neural stem cells are present throughout the development of the central nervous
system (CNS), persist into adulthood in defined locations and can be derived from more …

Large numbers of new neurons are born continuously in the adult subventricular zone
(SVZ). The molecular niche of SVZ stem cells is poorly understood. Here, we show that the …

Since descriptions of neural precursor cells (NPCs) were published in the late 19th century,
neuroanatomists have used a variety of terms to describe these cells, each term reflecting …

The discovery that the adult mammalian brain creates new neurons from pools of stemlike
cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural …

Bromodeoxyuridine (BrdU) is a thymidine analog that incorporates DNA of dividing cells
during the S-phase of the cell cycle. As such, BrdU is used for birth dating and monitoring …