[HTML][HTML] The role of diacylglycerol kinase in the amelioration of diabetic nephropathy

D Hayashi, Y Shirai - Molecules, 2022 - mdpi.com
The drastic increase in the number of patients with diabetes and its complications is a global
issue. Diabetic nephropathy, the leading cause of chronic kidney disease, significantly …

[HTML][HTML] Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis

BM Lane, M Chryst-Stangl, G Wu, M Shalaby… - JCI insight, 2022 - ncbi.nlm.nih.gov
We performed next-generation sequencing in patients with familial steroid-sensitive
nephrotic syndrome (SSNS) and identified a homozygous segregating variant (p. H310Y) in …

Vitamin E functions by association with a novel binding site on the 67 kDa laminin receptor activating diacylglycerol kinase

D Hayashi, VD Mouchlis, S Okamoto, T Namba… - The Journal of nutritional …, 2022 - Elsevier
It is generally recognized that the main function of α-tocopherol (αToc), which is the most
active form of vitamin E, is its antioxidant effect, while non-antioxidant effects have also been …

[HTML][HTML] The mechanisms of ameliorating effect of a green tea polyphenol on diabetic nephropathy based on diacylglycerol kinase α

D Hayashi, L Wang, S Ueda, M Yamanoue… - Scientific Reports, 2020 - nature.com
Significant efforts have been made to ameliorate diabetic nephropathy (DN) by inhibiting
protein kinase C. However, these efforts have not been successful in human trials …

The effect of antioxidant vitamins on patients with diabetes and albuminuria: a meta-analysis of randomized controlled trials

J Chen, J Wu, D Kong, C Yang, H Yu, Q Pan… - Journal of Renal …, 2020 - Elsevier
Objective This study aimed to investigate the effect of antioxidant vitamins, including
vitamins E and C, on patients with diabetes and albuminuria by conducting a meta-analysis …

[PDF][PDF] Effects of alpha-tocopherol on acute pancreatitis in rats.

H Özgül, C Tatar, B Özer, H Aydın… - Turkish Journal of …, 2019 - jag.journalagent.com
ABSTRACT BACKGROUND: Acute pancreatitis is a disease with high morbidity and
mortality, despite all the advances in technology. The overall mortality rate of acute …

小檗碱预防性治疗糖尿病肾病的研究进展

张雅晨, 孙建国 - 药学进展, 2023 - pps.cpu.edu.cn
糖尿病肾病是糖尿病微血管并发症之一, 其发病机制复杂, 与糖脂代谢紊乱, 炎症, 氧化应激,
自噬受损, 肠道菌群失调等因素交叉关联, 也是导致终末期肾病的主要原因. 综述了糖尿病肾病的 …

Direct Pharmacological Correction of Oxidative Stress in Rat Kidneys Does Not Facilitate Diabetic Nephropathy

AY Zharikov, SO Filinova, ON Mazko… - International Journal of …, 2021 - elibrary.ru
The aim of this study was to evaluate the effect of alpha-tocopherol acetate (ATA) on the
activity of free-radical oxidation (FRO) in renal tissue and renal function in rats with …

Research Progress of Berberine in Prophylactic Treatment of Diabetic Nephropathy

Z Yachen, SUN Jianguo - Progress in Pharmaceutical Sciences, 2023 - pps.cpu.edu.cn
Diabetic nephropathy is one of the microvascular complications of diabetes mellitus. Its
pathogenesis is complex and crosslinked with factors including glucolipid metabolism …

Almond Skin Polyphenol Extracts Stimulate the Activation of Diacylglycerol Kinase alpha via a 67 kDa Laminin Receptor

B Chinthammit, S Okamoto, Y Shirai - Functional Foods in Health and …, 2022 - ffhdj.com
Background: Almond skins are the byproduct of the almond industry that are rich in dietary
fibers and polyphenols. Recently, there has been an increasing interest in utilizing the …