Vaginal microbiome and cervical cancer

M Kyrgiou, AB Moscicki - Seminars in Cancer Biology, 2022 - Elsevier
The female reproductive tract, similar to other mucosal sites, harbors a specific microbiome
commonly dominated by Lactobacillus species (spp.), which has an essential role in …

Role of immunity and vaginal microbiome in clearance and persistence of human papillomavirus infection

L Ntuli, A Mtshali, G Mzobe, LJP Liebenberg… - Frontiers in cellular …, 2022 - frontiersin.org
Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

Host and environmental factors influencing individual human cytokine responses

R Ter Horst, M Jaeger, SP Smeekens, M Oosting… - Cell, 2016 - cell.com
Differences in susceptibility to immune-mediated diseases are determined by variability in
immune responses. In three studies within the Human Functional Genomics Project, we …

Genital inflammation and the risk of HIV acquisition in women

L Masson, JAS Passmore, LJ Liebenberg… - Clinical Infectious …, 2015 - academic.oup.com
Abstract Background. Women in Africa, especially young women, have very high human
immunodeficiency virus (HIV) incidence rates that cannot be fully explained by behavioral …

SPERANZA project: HPV vaccination after treatment for CIN2+

A Ghelardi, F Parazzini, F Martella, A Pieralli, P Bay… - Gynecologic …, 2018 - Elsevier
Results From January 2013, all women diagnosed with a CIN2+ cervical lesion/stage IA1
cervical cancer treated with cervical conization in the Department of Obstetrics and …

Link between chronic inflammation and human papillomavirus-induced carcinogenesis

JV Fernandes… - Oncology …, 2015 - spandidos-publications.com
Inflammation is a defense strategy against invading agents and harmful molecules that is
activated immediately following a stimulus, and involves the release of cytokines and …

Adjuvant HPV vaccination to prevent recurrent cervical dysplasia after surgical treatment: a meta-analysis

V Di Donato, G Caruso, M Petrillo, E Kontopantelis… - Vaccines, 2021 - mdpi.com
Objective: The aim of this meta-analysis was to discuss evidence supporting the efficacy of
adjuvant human papillomavirus (HPV) vaccination in reducing the risk of recurrent cervical …

Prophylactic HPV vaccination after conization: A systematic review and meta-analysis

M Jentschke, J Kampers, J Becker, P Sibbertsen… - Vaccine, 2020 - Elsevier
Introduction Human papillomavirus (HPV) vaccination is essential for cervical cancer
prevention. However, the value of HPV vaccination in the context excisional treatment of …

Effect of human papillomavirus infection on the immune system and its role in the course of cervical cancer

D Song, H Li, H Li, J Dai - Oncology letters, 2015 - spandidos-publications.com
Human papillomavirus (HPV) is widely known as a cause of cervical intraepithelial
neoplasia (CIN) and cervical cancer. The mechanisms involved have been studied by …

Adjuvant human papillomavirus vaccine to reduce recurrent cervical dysplasia in unvaccinated women: a systematic review and meta-analysis

K Lichter, D Krause, J Xu, SHL Tsai, C Hage… - Obstetrics & …, 2020 - journals.lww.com
OBJECTIVE: To perform a systematic review and meta-analysis evaluating the efficacy of
adjuvant human papillomavirus (HPV) vaccination in preventing recurrent cervical …