Characterizing metabolism in cancer is crucial for understanding tumor biology and for
developing potential therapies. Although most metabolic investigations analyze averaged …

Cluster secondary ion mass spectrometry (cluster SIMS) has played a critical role in the
characterization of polymeric materials over the last decade, allowing for the ability to obtain …

Organic vapor deposited thin films of pure biomolecules, polymer films and biomolecules
dispersed in gelatin and biological tissue have been analyzed in a magnetic sector …

Peptide-doped trehalose thin films have been characterized by bombardment with energetic
cluster ion beams of C60+ and Au x+(x= 1, 2, 3). The aim of these studies is to acquire …

In principle mass spectral imaging has enormous potential for discovery applications in
biology. The chemical specificity of mass spectrometry combined with spatial analysis …

A buckminsterfullerene ion source is employed to characterize peptide-doped trehalose thin
films. The experiments are designed to utilize the unique sputtering properties of cluster ion …

A brief review is given regarding the application of cluster ion beams as desorption probes
in molecular SIMS. The general observation is that the efficiency of secondary ion formation …

Secondary ion mass spectrometry (SIMS) has become a powerful technique for the label-
free analysis of organics from cells to electronic devices. The development of cluster ion …

With the implementation of focused primary ion beams, secondary ion mass spectrometry
(SIMS) has become a significant technique in the rapidly emerging field of mass spectral …

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) provides a method for the
detection of native and exogenous compounds in biological samples on a cellular scale …