Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …

Natural products and their molecular frameworks have a long tradition as valuable starting
points for medicinal chemistry and drug discovery. Recently, there has been a revitalization …

The unprecedented use of antibiotics that led to development of resistance affect human
health worldwide. Prescription of antibiotics imprudently and irrationally in different diseases …

Agonists of the nuclear receptor PPARγ are therapeutically used to combat hyperglycaemia
associated with the metabolic syndrome and type 2 diabetes. In spite of being effective in …

Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …

Natural products have always been exploited to promote health and served as a valuable
source for the discovery of new drugs. In this review, the great potential of natural …

Nuclear receptors (NRs) represent attractive targets for the treatment of metabolic syndrome-
related diseases. In addition, natural products are an interesting pool of potential ligands …

Skeletal muscle (SM) plays a vital role in energy and glucose metabolism by regulating
insulin sensitivity, glucose uptake, and blood glucose homeostasis. Impaired SM …

Over years, various biological constituents are isolated from Traditional Chinese Medicine
and confirmed to show multifunctional activities. Magnolol, a hydroxylated biphenyl natural …

Background Peroxisome proliferator-activated receptor gamma (PPARγ) agonists are
clinically used to counteract hyperglycemia. However, so far experienced unwanted side …