The impact of prenatal alcohol exposure on social, cognitive and affective behavioral domains: Insights from rodent models

K Marquardt, JL Brigman - Alcohol, 2016 - Elsevier
Abstract Fetal Alcohol Spectrum Disorders (FASD) are characterized by deficits in working
memory, response inhibition, and behavioral flexibility. However, the combination and …

Preclinical methodological approaches investigating of the effects of alcohol on perinatal and adolescent neurodevelopment

CDC Bailey, R Gerlai, NM Cameron… - Neuroscience & …, 2020 - Elsevier
Despite much evidence of its economic and social costs, alcohol use continues to increase.
Much remains to be known as to the effects of alcohol on neurodevelopment across the …

Transgenerational transmission of the effect of gestational ethanol exposure on ethanol use‐related behavior

ME Nizhnikov, DO Popoola… - Alcoholism: Clinical and …, 2016 - Wiley Online Library
Background Prenatal alcohol exposure (PAE) enhances the risk for alcoholism by
increasing the propensity to consume alcohol and altering neurophysiological response to …

Prenatal stress induces long-term behavioral sex-dependent changes in rats offspring: the role of the HPA axis and epigenetics

T Possamai-Della, JH Cararo, JM Aguiar-Geraldo… - Molecular …, 2023 - Springer
Preclinical genetic studies have related stress early exposures with changes in gene
regulatory mechanisms, including epigenetic alterations, such as modifications of DNA …

Prenatal alcohol exposure as a case of involuntary early onset of alcohol use: consequences and proposed mechanisms from animal studies

M Gaztañaga, A Angulo-Alcalde… - Frontiers in behavioral …, 2020 - frontiersin.org
Prenatal alcohol exposure has been found to be an important factor determining later
consumption of this drug. In humans, despite the considerable diversity of variables that …

Low doses of prenatal ethanol exposure and maternal separation alter HPA axis function and ethanol consumption in adult male rats

F Biggio, G Talani, V Locci, MG Pisu, G Boero… - …, 2018 - Elsevier
Adverse maternal behaviors during pregnancy and unfavorable postnatal experiences
during development are associated with an increased risk of developing psychiatric …

Combined effect of gestational stress and postpartum stress on maternal care in rats

G Boero, F Biggio, MG Pisu, V Locci, P Porcu… - Physiology & …, 2018 - Elsevier
Variations in maternal care in the rat influence the development of individual differences in
behavioral and endocrine responses to stress. This study aimed to examine the interaction …

Juvenile social isolation affects maternal care in rats: involvement of allopregnanolone

MG Pisu, G Boero, F Biggio, A Garau, D Corda… - …, 2017 - Springer
Rationale Social isolation of rats immediately after weaning is thought to represent an
animal model of anxiety-like disorders. Socially isolated virgin females showed a significant …

Effects of paternal predation risk and rearing environment on maternal investment and development of defensive responses in the offspring

AC Korgan, E O'Leary, J Bauer, A Fortier, ICG Weaver… - Eneuro, 2016 - eneuro.org
Detecting past experiences with predators of a potential mate informs a female about
prevailing ecological threats, in addition to stress-induced phenotypes that may be …

Cross-generational THC exposure alters heroin reinforcement in adult male offspring

BJ Hempel, ME Crissman, A Imanalieva… - Drug and Alcohol …, 2020 - Elsevier
Background An emerging area of preclinical research has investigated whether drug use in
parents prior to conception influences drug responsivity in their offspring. The present work …