The chemistry and biological activities of peptides from amphibian skin secretions
X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …
environmental factors including microorganisms, parasites, predators, and physical factors …
Rationalizing the membrane interactions of cationic amphipathic antimicrobial peptides by their molecular shape
B Bechinger - Current Opinion in Colloid & Interface Science, 2009 - Elsevier
Biophysical and structural studies of cationic amphipathic antimicrobial peptides have
revealed new mechanistic details concerning their membrane interactions. In interfacial …
revealed new mechanistic details concerning their membrane interactions. In interfacial …
DADP: the database of anuran defense peptides
M Novković, J Simunić, V Bojović, A Tossi… - …, 2012 - academic.oup.com
Anuran tissues, and especially skin, are a rich source of bioactive peptides and their
precursors. We here present a manually curated database of antimicrobial and other …
precursors. We here present a manually curated database of antimicrobial and other …
[HTML][HTML] Structure and topology of the huntingtin 1–17 membrane anchor by a combined solution and solid-state NMR approach
M Michalek, ES Salnikov, B Bechinger - Biophysical journal, 2013 - cell.com
The very amino-terminal domain of the huntingtin protein is directly located upstream of the
protein's polyglutamine tract, plays a decisive role in several important properties of this …
protein's polyglutamine tract, plays a decisive role in several important properties of this …
ATP synthase: a molecular therapeutic drug target for antimicrobial and antitumor peptides
Z Ahmad, F Okafor, S Azim… - Current medicinal …, 2013 - ingentaconnect.com
In this review we discuss the role of ATP synthase as a molecular drug target for natural and
synthetic antimicrobial/antitumor peptides. We start with an introduction of the universal …
synthetic antimicrobial/antitumor peptides. We start with an introduction of the universal …
A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies
MH Cardoso, ES Candido, LY Chan… - ACS infectious …, 2018 - ACS Publications
Computer-aided screening of antimicrobial peptides (AMPs) is a promising approach for
discovering novel therapies against multidrug-resistant bacterial infections. Here, we …
discovering novel therapies against multidrug-resistant bacterial infections. Here, we …
Mechanism of antibacterial action of dermaseptin B2: Interplay between helix− hinge− helix structure and membrane curvature strain
C Galanth, F Abbassi, O Lequin, J Ayala-Sanmartin… - Biochemistry, 2009 - ACS Publications
Dermaseptin B2 (Drs B2) is a 33-residue-long cationic, α-helical antimicrobial peptide
endowed with membrane-damaging activity against a broad spectrum of microorganisms …
endowed with membrane-damaging activity against a broad spectrum of microorganisms …
[HTML][HTML] PEGylation of the antimicrobial peptide LyeTx Ib maintains structure-related biological properties and improves selectivity
JC Moreira Brito, LR Carvalho… - Frontiers in Molecular …, 2022 - frontiersin.org
The biological activity of antimicrobial peptides and proteins is closely related to their
structural aspects and is sensitive to certain post-translational modifications such as …
structural aspects and is sensitive to certain post-translational modifications such as …
The structural and topological analysis of membrane-associated polypeptides by oriented solid-state NMR spectroscopy: established concepts and novel …
B Bechinger, JM Resende, C Aisenbrey - Biophysical chemistry, 2011 - Elsevier
Solid-state NMR spectroscopy is a powerful technique for the investigation of membrane-
associated peptides and proteins as well as their interactions with lipids, and a variety of …
associated peptides and proteins as well as their interactions with lipids, and a variety of …
Molecular mechanism of antimicrobial excipient-induced aggregation in parenteral formulations of peptide therapeutics
Antimicrobial preservatives are used as functional excipients in multidose formulations of
biological therapeutics to destroy or inhibit the growth of microbial contaminants, which may …
biological therapeutics to destroy or inhibit the growth of microbial contaminants, which may …