Current high‐throughput screening methods for drug discovery rely on the existence of
targets. Moreover, most of the hits generated during screenings turn out to be invalid after …

Introduction: Duchenne muscular dystrophy (DMD) is an X-linked handicapping disease due
to the loss of an essential muscle protein dystrophin. Dystrophin-null animals have been …

Despite the recent progress in the broad‐scaled analysis of proteins in body fluids, there is
still a lack in protein profiling approaches for biomarkers of rare diseases. Scarcity of …

Mitochondrial dysfunction has been recognized as an early event in Alzheimer's disease
(AD) pathology, preceding and inducing neurodegeneration and memory loss. The …

Objective: In boys with Duchenne muscular dystrophy (DMD), 1H MRI suggested muscular
edema before fatty degeneration. Using specific 23Na MRI sequences, we tested the …

Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy. In the
present study, when human induced pluripotent stem cells (hiPSCs) were differentiated into …

Defects in neuronal connectivity of the brain are well documented among schizophrenia
patients. Although the schizophrenia susceptibility gene Disrupted-in-Schizophrenia 1 …

Spinal muscular atrophy (SMA), an autosomal recessive genetic disorder, is characterized
by the selective degeneration of lower motor neurons, leading to muscle atrophy and, in the …

Duchenne muscular dystrophy (DMD) is a genetic disease characterized by progressive
muscle degeneration due to mutations in the dystrophin gene. In spite of great advances in …

Duchenne muscular dystrophy (DMD) is a neuromuscular disease caused by mutations in
the dystrophin gene. The subcellular mechanisms of DMD remain poorly understood and …