Ochratoxin A-induced nephrotoxicity: Up-to-date evidence

CS Khoi, JH Chen, TY Lin, CK Chiang… - International journal of …, 2021 - mdpi.com
Ochratoxin A (OTA) is a mycotoxin widely found in various foods and feeds that have a
deleterious effect on humans and animals. It has been shown that OTA causes multiorgan …

Interplay between Zn2+ Homeostasis and Mitochondrial Functions in Cardiovascular Diseases and Heart Ageing

SA Dabravolski, NK Sadykhov, AG Kartuesov… - International Journal of …, 2022 - mdpi.com
Zinc plays an important role in cardiomyocytes, where it exists in bound and histochemically
reactive labile Zn2+ forms. Although Zn2+ concentration is under tight control through …

[HTML][HTML] Vascular protection afforded by zinc supplementation in human coronary artery smooth muscle cells mediated by NRF2 signaling under hypoxia …

F Yang, MJ Smith, A Griffiths, A Morrell, SJ Chapple… - Redox biology, 2023 - Elsevier
Zinc (Zn) has antioxidant, anti-inflammatory and anti-proliferative actions, with Zn
dysregulation associated with coronary ischemia/reperfusion injury and smooth muscle cell …

Male Reproductive Toxicity of Antifouling Chemicals: Insights into Oxidative Stress-Induced Infertility and Molecular Mechanisms of Zinc Pyrithione (ZPT)

MJ Panga, Y Zhao - Antioxidants, 2024 - mdpi.com
Zinc pyrithione (ZPT), a widely utilized industrial chemical, is recognized for its versatile
properties, including antimicrobial, antibacterial, antifungal, and antifouling activities …

Metal-binding proteins cross-linking with endoplasmic reticulum stress in cardiovascular diseases

K Li, Y Li, H Ding, J Chen, X Zhang - Journal of Cardiovascular …, 2023 - mdpi.com
The endoplasmic reticulum (ER), an essential organelle in eukaryotic cells, is widely
distributed in myocardial cells. The ER is where secreted protein synthesis, folding, post …

Adjuvant therapy with zinc supplementation; anti-inflammatory and anti-oxidative role in multiple myeloma patients receiving autologous hematopoietic stem cell …

K Jahankhani, N Taghipour, M Nikoonezhad… - BioMetals, 2024 - Springer
Multiple myeloma (MM) patients are often accompanied by heightened levels of oxidative
stress, even following bone marrow transplantation. Trace mineral supplements have been …

Zinc ionophores isolated from Terminalia bellirica fruit rind extract protect against cardiomyocyte hypoxia/reoxygenation injury

VL Bodiga, PK Vemuri, MR Kudle, S Bodiga - Bioorganic & Medicinal …, 2021 - Elsevier
The study aimed to isolate and characterize zinc ionophores from Terminalia bellirica fruit
using a liposome assay and test its utility in H9c2 rat cardiomyoblasts cells subjected to …

2-hydroxy-4-methoxy benzaldehyde from Hemidesmus indicus root extract suppresses toll-like receptor2-mediated migration and invasive mechanisms in rheumatoid …

MK Durgam, VL Bodiga, PK Vemuri, VR Aenugu… - Journal of Herbal …, 2023 - Elsevier
Abstract Introduction Elevated expression of Toll-like receptor2 (TLR2) in synovial
fibroblasts, endothelial and other infiltrating cells in rheumatoid arthritis promotes their …

[PDF][PDF] Zinc Depletion Inhibits the Synthesis and Secretion of Thyroglobulin by Inducing Endoplasmic Reticulum Stress in PCCL3 Thyroid Cells

K Kwon, ER Lee, KH Kang, TS Hwang… - … Journal of Biology …, 2022 - npublications.com
Thyroglobulin (Tg) is essential for thyroid hormone synthesis and thyroid function. Its levels
are regulated by external environmental changes. Zinc is widely involved in cellular …

Investigating the Effects of Zinc (Zn) Supplementation on the Levels of Oxidative Stress and Inflammation Markers in Multiple Myeloma Patients Undergoing …

K Jahankhani, H Behboudi… - … in Medicine: Journal …, 2023 - search.ebscohost.com
Abstract Background and Aim: Many cancer patients suffer from irreparable complications
under the influence of oxidative stress. The administration of effective supplements to control …