Pharmacological Activities, Therapeutic Effects, and Mechanistic Actions of Trigonelline
Trigonelline (TRG) is a natural polar hydrophilic alkaloid that is found in many plants such as
green coffee beans and fenugreek seeds. TRG potentially acts on multiple molecular …
green coffee beans and fenugreek seeds. TRG potentially acts on multiple molecular …
Trigonelline as an anticonvulsant agent: mechanistic insights into NMDA receptor expression and oxidative stress balance
N Kabiri-Samani, H Amini-Khoei, M Rahimi-Madiseh… - Scientific Reports, 2024 - nature.com
Glutamatergic neurotransmission and oxidative stress are involved in the pathophysiology of
seizures. Some anticonvulsants exert their effects through modulation of these pathways …
seizures. Some anticonvulsants exert their effects through modulation of these pathways …
Molecular Docking Analysis Reveals the Promising Role of Apigenin as a Potential Treatment for Neurological Disorders
M Wasim, SR Zia, S Ahmad - Clinical Neuropharmacology, 2024 - journals.lww.com
Objectives Neurological disorders represent a significant global health challenge,
necessitating the exploration of novel therapeutic agents. Apigenin, a natural flavonoid …
necessitating the exploration of novel therapeutic agents. Apigenin, a natural flavonoid …
A Systematic Review on the Effectiveness of Trigonelline, Safranal and Chamomile in Cure and Prevention of Alzheimer's Disease and Dementia
A Tahir, S Khan, M Wasim, S Ahmad - Neurochemical Journal, 2024 - Springer
Alzheimer's disease and dementia are neurodegenerative conditions characterized by
memory loss and diminished capacity to perform daily tasks. These disorders pose a …
memory loss and diminished capacity to perform daily tasks. These disorders pose a …
Safranal's Neurological Nexus: Unveiling Therapeutic Potential through Molecular Docking
M Wasim, SR Zia, S Ahmad - Neurochemical Journal, 2024 - Springer
Safranal, a bioactive compound derived from saffron, has emerged as a subject of growing
interest in the quest for novel therapeutics targeting neurological disorders. This research …
interest in the quest for novel therapeutics targeting neurological disorders. This research …
Coffee and Alzheimer's disease
F Mirzaei, L Agbaria, K Bhatnagar… - Progress in brain …, 2024 - pubmed.ncbi.nlm.nih.gov
Coffee, a universally consumed beverage, is known to contain thousands of bioactive
constituents that have garnered interest due to their potential neuroprotective effects against …
constituents that have garnered interest due to their potential neuroprotective effects against …