Itch: from mechanism to (novel) therapeutic approaches
G Yosipovitch, JD Rosen, T Hashimoto - Journal of allergy and clinical …, 2018 - Elsevier
Itch is a common sensory experience that is prevalent in patients with inflammatory skin
diseases, as well as in those with systemic and neuropathic conditions. In patients with …
diseases, as well as in those with systemic and neuropathic conditions. In patients with …
Mediators of chronic pruritus in atopic dermatitis: getting the itch out?
NK Mollanazar, PK Smith, G Yosipovitch - Clinical reviews in allergy & …, 2016 - Springer
For centuries, itch was categorized as a submodality of pain. Recent research over the last
decade has led to the realization that itch is in fact a separate and distinct, albeit closely …
decade has led to the realization that itch is in fact a separate and distinct, albeit closely …
International comparisons of prevalence, awareness, and treatment of pruritus in people on hemodialysis
HC Rayner, M Larkina, M Wang… - Clinical journal of the …, 2017 - journals.lww.com
Results Patients very much or extremely bothered by itching declined from 28% in 1996 to
18% in 2015. In 2012–2015, among patients nearly always or always bothered by itching …
18% in 2015. In 2012–2015, among patients nearly always or always bothered by itching …
[HTML][HTML] Self-reported pruritus and clinical, dialysis-related, and patient-reported outcomes in hemodialysis patients
N Sukul, A Karaboyas, PA Csomor, T Schaufler, W Wen… - Kidney medicine, 2021 - Elsevier
Rationale & Objective Chronic kidney disease (CKD)-associated pruritus, generalized
itching related to CKD, affects many aspects of hemodialysis patients' lives. However …
itching related to CKD, affects many aspects of hemodialysis patients' lives. However …
The vicious cycle of itch and anxiety
KM Sanders, T Akiyama - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
Chronic itch is associated with increased stress, anxiety, and other mood disorders. In turn,
stress and anxiety exacerbate itch, leading to a vicious cycle that affects patient behavior …
stress and anxiety exacerbate itch, leading to a vicious cycle that affects patient behavior …
Sleep disorders, restless legs syndrome, and uremic pruritus: diagnosis and treatment of common symptoms in dialysis patients
JS Scherer, SA Combs, F Brennan - American Journal of Kidney Diseases, 2017 - Elsevier
Maintenance dialysis patients experience a high burden of physical and emotional
symptoms that directly affect their quality of life and health care utilization. In this review, we …
symptoms that directly affect their quality of life and health care utilization. In this review, we …
Multi-modal clique-graph matching for view-based 3D model retrieval
Multi-view matching is an important but a challenging task in view-based 3D model retrieval.
To address this challenge, we propose an original multi-modal clique graph (MCG) …
To address this challenge, we propose an original multi-modal clique graph (MCG) …
Clinical presentation, management, and pathophysiology of neuropathic itch
M Steinhoff, M Schmelz, IL Szabó… - The Lancet …, 2018 - thelancet.com
Unlike conventional itch, neuropathic itch develops in normal skin from excess peripheral
firing or dampened central inhibition of itch pathway neurons. Neuropathic itch is a symptom …
firing or dampened central inhibition of itch pathway neurons. Neuropathic itch is a symptom …
Dorsal horn gastrin-releasing peptide expressing neurons transmit spinal itch but not pain signals
GW Albisetti, M Pagani, E Platonova… - Journal of …, 2019 - Soc Neuroscience
Gastrin-releasing peptide (GRP) is a spinal itch transmitter expressed by a small population
of dorsal horn interneurons (GRP neurons). The contribution of these neurons to spinal itch …
of dorsal horn interneurons (GRP neurons). The contribution of these neurons to spinal itch …
Human lesions and animal studies link the claustrum to perception, salience, sleep and pain
The claustrum is the most densely interconnected region in the human brain. Despite the
accumulating data from clinical and experimental studies, the functional role of the claustrum …
accumulating data from clinical and experimental studies, the functional role of the claustrum …