Bacterial biofilms are complex microbial communities encased in extracellular polymeric
substances. Their formation is a multi-step process. Biofilms are a significant problem in …

A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix
produced by themselves. Many types of microorganisms that are found on living hosts or in …

As we step into the post-antibiotic era, the accelerated emergence of antibiotic-resistant
pathogenic bacteria poses an increasingly serious threat to public health. The formation of …

Bacterial infection by ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp.) …

The rise in antibiotic-resistant strains of clinically important pathogens is a major threat to
global health. The World Health Organization (WHO) has recognized the urgent need to …

Cell-penetrating peptides (CPPs) allow intracellular delivery of bioactive cargo molecules.
The mechanisms allowing CPPs to enter cells are ill-defined. Using a CRISPR/Cas9-based …

Typical antibiotic treatments are often ineffectual against biofilm-related infections since
bacteria residing within biofilms have developed various mechanisms to resist antibiotics. To …

Despite antimicrobial resistance, which is attributed to the misuse of broad-spectrum
antibiotics, antibiotics can indiscriminately kill pathogenic and beneficial microorganisms …

Multi drug-resistant Gram-positive pathogens have become one of the most serious
problems facing humankind today. To address this challenge, there is an urgent need to …

Background Bacterial biofilms generally contribute to chronic infections and complicate
effective treatment outcomes. To date, there have been no reports describing biofilm …