Recent advances in γH2AX biomarker-based genotoxicity assays: A marker of DNA damage and repair

N Rahmanian, M Shokrzadeh, M Eskandani - DNA repair, 2021 - Elsevier
The phosphorylation of histone variant H2AX and formation of γH2AX is a primary response
to the DNA double-strand breaks (DSBs). Detection of γH2AX is a robust and sensitive tool …

Potential application of γ-H2AX as a biodosimetry tool for radiation triage

V Raavi, V Perumal, SFD Paul - Mutation Research/Reviews in Mutation …, 2021 - Elsevier
Radiation triage and biological dosimetry are two initial steps in the medical management of
exposed individuals following radiological accidents. Well established biodosimetry …

DNA Damage in Blood Leukocytes of Prostate Cancer Patients Undergoing PET/CT Examinations with [68Ga]Ga-PSMA I&T

S Schumann, H Scherthan, T Frank, C Lapa, J Müller… - Cancers, 2020 - mdpi.com
The aim was to investigate the induction and repair of radiation-induced DNA double-strand
breaks (DSBs) as a function of the absorbed dose to the blood of patients undergoing …

The efficacy of photobiomodulation therapy in improving tissue resilience and healing of radiation skin damage

RC Mosca, SN Santos, GEC Nogueira, DL Pereira… - Photonics, 2021 - mdpi.com
The increased precision, efficacy, and safety of radiation brachytherapy has tremendously
improved its popularity in cancer care. However, an unfortunate side effect of this therapy …

Exposure of patients to low doses of X-radiation during neuro-interventional imaging and procedures: Dose estimation and analysis of γ-H2AX foci and gene …

S Visweswaran, S Joseph, J Dhanasekaran… - … /Genetic Toxicology and …, 2020 - Elsevier
Radiation has widespread applications in medicine. However, despite the benefits of
medical radiation exposures, adverse long-term health effects are cause for concern. Protein …

Cumulative Dose from Recurrent CT Scans: Exploring the DNA Damage Response in Human Non-Transformed Cells

D Valente, MP Gentileschi, A Valenti, M Burgio… - International Journal of …, 2024 - mdpi.com
Recurrent computed tomography (CT) examination has become a common diagnostic
procedure for several diseases and injuries. Though each singular CT scan exposes …

Detection and characterization of musculoskeletal cancer using whole-body magnetic resonance imaging

A Isaac, F Lecouvet, D Dalili, L Fayad… - Seminars in …, 2020 - thieme-connect.com
Whole-body magnetic resonance imaging (WB-MRI) is gradually being integrated into
clinical pathways for the detection, characterization, and staging of malignant tumors …

Candidate gene expression in regional population and its relevance for radiation triage

N Kannan, T Koshy, V Raavi, E Bhaskar… - … and Genome Research, 2023 - karger.com
Quantification of gene expression signatures has been substantiated as a potential and
rapid marker for radiation triage and biodosimetry during nuclear emergencies. Similar to …

Changes in Radiosensitivity to Gamma-Rays of Lymphocytes from Hyperthyroid Patients Treated with I-131

V Dini, M Salvatori, M Belli, ME Lago, A Nosdeo… - International Journal of …, 2022 - mdpi.com
This study investigated the peripheral blood lymphocytes (PBL) response to a dose of γ-rays
in patients treated with radioiodine (I-131) for hyperthyroidism vs. healthy controls, to gain …

A Lightweight Low-dose PET Image Super-resolution Reconstruction Method based on Convolutional Neural Network

K Liu, H Yu, M Zhang, L Zhao, X Wang… - Current Medical …, 2023 - ingentaconnect.com
Background: PET imaging is one of the most widely used neurological disease screening
and diagnosis techniques. Aims: Since PET involves the radiation and tolerance of different …