Advances in Spheroids and Organoids on a Chip

G Fang, YC Chen, H Lu, D Jin - Advanced Functional Materials, 2023 - Wiley Online Library
Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …

Regenerating eye tissues to preserve and restore vision

JH Stern, Y Tian, J Funderburgh, G Pellegrini, K Zhang… - Cell stem cell, 2018 - cell.com
Ocular regenerative therapies are on track to revolutionize treatment of numerous blinding
disorders, including corneal disease, cataract, glaucoma, retinitis pigmentosa, and age …

Assembling living building blocks to engineer complex tissues

L Ouyang, JPK Armstrong… - Advanced Functional …, 2020 - Wiley Online Library
The great demand for tissue and organ grafts, compounded by an aging demographic and a
shortage of available donors, has driven the development of bioengineering approaches …

3D culture systems for exploring cancer immunology

AA Fitzgerald, E Li, LM Weiner - Cancers, 2020 - mdpi.com
Simple Summary To study any disease, researchers need convenient and relevant disease
models. In cancer, the most commonly used models are two-dimensional (2D) culture …

Dissolvable microgel-templated macroporous hydrogels for controlled cell assembly

Z Jiang, FY Lin, K Jiang, H Nguyen, CY Chang… - Biomaterials …, 2022 - Elsevier
Mesenchymal stem cells (MSCs)-based therapies have been widely used to promote tissue
regeneration and to modulate immune/inflammatory response. The therapeutic potential of …

Programmable Electrodeposition of Janus Alginate/Poly‐L‐Lysine/Alginate (APA) Microcapsules for High‐Resolution Cell Patterning and Compartmentalization

Z Liu, H Nan, Y Jiang, T Xu, X Gong, C Hu - Small, 2022 - Wiley Online Library
Encapsulation of live cells in protective, semipermeable microcapsules is one of the kernel
techniques for in vitro tissue regeneration, cell therapies, and pharmaceutical screening …

[HTML][HTML] Inner ear organoids: recent progress and potential applications

Y Lou, Y Liu, M Wu, G Jia, M Xia, W Li - Fundamental Research, 2023 - Elsevier
The inner ear is one of the most complicated structures that harbor organs for the perception
of sound and balance, which is deep in the temporal bone and challenging to operate …

Engineering Tissues without the Use of a Synthetic Scaffold: A Twenty‐Year History of the Self‐Assembly Method

I Saba, W Jakubowska, S Bolduc… - BioMed Research …, 2018 - Wiley Online Library
Twenty years ago, Dr. François A. Auger, the founder of the Laboratory of Experimental
Organogenesis (LOEX), introduced the self‐assembly technique. This innovative technique …

Gelatin Hydrogels Reinforced by Absorbable Nanoparticles and Fibrils Cured In Situ by Visible Light for Tissue Adhesive Applications

SM Wei, MY Pei, WL Pan, H Thissen, SW Tsai - Polymers, 2020 - mdpi.com
Most gelatin hydrogels used in regenerative medicine applications today are fabricated by
photocrosslinking due to the convenience and speed of this method. However, in most …

Utilizing bioprinting to engineer spatially organized tissues from the bottom-up

Y Zhan, W Jiang, Z Liu, Z Wang, K Guo… - Stem Cell Research & …, 2024 - Springer
In response to the growing demand for organ substitutes, tissue engineering has evolved
significantly. However, it is still challenging to create functional tissues and organs. Tissue …