Critical assessment of on-premise approaches to scalable genome analysis

A Al-Aamri, S Kamarul Azman, G Daw Elbait… - BMC …, 2023 - Springer
Background Plummeting DNA sequencing cost in recent years has enabled genome
sequencing projects to scale up by several orders of magnitude, which is transforming …

Potentially repurposable drugs for schizophrenia identified from its interactome

KB Karunakaran, S Chaparala, MK Ganapathiraju - Scientific reports, 2019 - nature.com
We previously presented the protein-protein interaction network of schizophrenia associated
genes, and from it, the drug-protein interactome which showed the drugs that target any of …

Analysis of transcript levels of a few schizophrenia candidate genes in neurons from a transgenic mouse embryonic stem cell model overexpressing DNMT1

S Saxena, PA Maroju, S Choudhury, A Anne… - Gene, 2020 - Elsevier
Abstract Overexpression of DNA Methyltransferase I (DNMT1) is considered as one of the
etiological factors for schizophrenia (SZ). However, information on genes subjected to …

Assessment of DDAH1 and DDAH2 contributions to psychiatric disorders via in silico methods

AA Kozlova, AN Vaganova, RN Rodionov… - International Journal of …, 2022 - mdpi.com
The contribution of nitric oxide synthases (NOSs) to the pathophysiology of several
neuropsychiatric disorders is recognized, but the role of their regulators, dimethylarginine …

[HTML][HTML] Interactome of SARS-CoV-2/nCoV19 modulated host proteins with computationally predicted PPIs

KB Karunakaran, N Balakrishnan… - Research …, 2020 - ncbi.nlm.nih.gov
World over, people are looking for solutions to tackle the pandemic coronavirus disease
(COVID-19) caused by the virus SARS-CoV-2/nCoV-19. Notable contributions in biomedical …

Effect of cannabidiol on schizophrenia based on randomized controlled trials: A meta-analysis

S Zhang, M Li, Z Guo - Annales Médico-psychologiques, revue …, 2022 - Elsevier
Studies and treatments of schizophrenia with cannabidiol (CBD) alone have been reported.
However, there have been a variety of different results of the effects of CBD in schizophrenic …

[引用][C] Dieses Dokument ist eine Zweitveröffentlichung (Verlagsversion) This is a self-archiving document (published version)

AA Kozlova, AN Vaganova, RN Rodionov