Neurogenesis and tumorigenesis share signaling molecules/pathways involved in cell
proliferation, differentiation, migration, and death. Self-renewal of neural stem cells is a …

Over the last decades, adult neurogenesis in the central nervous system (CNS) has
emerged as a fundamental process underlying physiology and disease. Recent evidence …

Transcriptome analysis by RNA-seq technology allows novel insights into gene expression
and regulatory networks in health and disease. To better understand the molecular basis of …

Stem cells can self-renew, differentiate, or enter quiescence. Understanding how stem cells
switch between these states is highly relevant for stem cell-based therapeutics. Drosophila …

Breast cancer is one of the most lethal malignancies in women worldwide and is
characterized by rapid growth and low survival rates, despite advances in tumor biology and …

Nervous system malignancies are characterized by rapid progression and poor survival
rates. These clinical observations underscore the need for novel therapeutic insights and …

The enormous complexity of mammalian central nervous system (CNS) is generated by
highly synchronized actions of diverse factors and signalling molecules in neural …

The developing central nervous system (CNS) is particularly prone to malignant
transformation, but the underlying mechanisms remain unresolved. However, periods of …

The histone variant macroH2A (mH2A) has been implicated in transcriptional repression, but
the molecular mechanisms that contribute to global mH2A-dependent genome regulation …

The field of bioactive lipids is ever expanding with discoveries of novel lipid molecules that
promote human health. Adopting a lipidomic-assisted approach, two new families of …