The homeostatic role of hydrogen peroxide, superoxide anion and nitric oxide in the vasculature

TJ Costa, PR Barros, C Arce, JD Santos… - Free Radical Biology …, 2021 - Elsevier
Reactive oxygen and nitrogen species are produced in a wide range of physiological
reactions that, at low concentrations, play essential roles in living organisms. There is a …

Current challenges and best practices for cell-free long RNA biomarker discovery

L Cabús, J Lagarde, J Curado, E Lizano… - Biomarker …, 2022 - Springer
The analysis of biomarkers in biological fluids, also known as liquid biopsies, is seen with
great potential to diagnose complex diseases such as cancer with a high sensitivity and …

Piwi-interacting RNAs (piRNAs) as potential biomarkers and therapeutic targets for cardiovascular diseases

M Li, Y Yang, Z Wang, T Zong, X Fu, LHH Aung… - Angiogenesis, 2021 - Springer
Cardiovascular diseases (CVDs) are the leading causes of death worldwide. Increasing
reports demonstrated that non-coding RNAs (ncRNAs) have been crucially involved in the …

Considerations and suggestions for the reliable analysis of miRNA in plasma using qRT-PCR

E Ban, EJ Song - Genes, 2022 - mdpi.com
MicroRNAs (miRNAs) are promising molecules that can regulate gene expression, and their
expression level and type have been associated with early diagnosis, targeted therapy, and …

The miRNome of depression

D Żurawek, G Turecki - International Journal of Molecular Sciences, 2021 - mdpi.com
Depression is an effect of complex interactions between genetic, epigenetic and
environmental factors. It is well established that stress responses are associated with …

[HTML][HTML] Non-coding RNAs as biomarkers of myocardial infarction

H Almaghrbi, R Giordo, G Pintus, H Zayed - Clinica Chimica Acta, 2023 - Elsevier
Non-coding RNAs (ncRNAs) encompass a family of ubiquitous RNA molecules that lack
protein-coding potential and have tissue-specific expression. A significant body of evidence …

LiKidMiRs: A ddPCR-based panel of 4 circulating miRNAs for detection of renal cell carcinoma

JP Sequeira, V Constâncio, S Salta, J Lobo… - Cancers, 2022 - mdpi.com
Simple Summary Early detection of renal cell carcinoma (RCC) significantly increases the
likelihood of curative treatment, avoiding the need of adjuvant therapies, associated side …

From multi-omics approaches to personalized medicine in myocardial infarction

C Zhan, T Tang, E Wu, Y Zhang, M He, R Wu… - Frontiers in …, 2023 - frontiersin.org
Myocardial infarction (MI) is a prevalent cardiovascular disease characterized by myocardial
necrosis resulting from coronary artery ischemia and hypoxia, which can lead to severe …

Sepsis encephalopathy is partly mediated by miR370-3p-induced mitochondrial injury but attenuated by BAM15 in cecal ligation and puncture sepsis male mice

P Hiengrach, P Visitchanakun… - International Journal of …, 2022 - mdpi.com
BAM15 (a mitochondrial uncoupling agent) was tested on cecal ligation and puncture (CLP)
sepsis mice with in vitro experiments. BAM15 attenuated sepsis as indicated by survival …

Circulating microRNA biomarkers in melanoma and non-melanoma skin cancer

G Durante, E Broseghini, F Comito… - Expert Review of …, 2022 - Taylor & Francis
Introduction Skin cancer is the most common type of cancer and is classified in melanoma
and non-melanoma cancers, which include basal cell, squamous cell, and Merkel cell …