New Findings What is the topic of this review? This review examines the notion that
obstructive sleep apnoea (OSA) and intermittent hypoxia (IH) have hormetic effects on …

Sleep apnea (SA) is a very prevalent sleep breathing disorder mainly characterized by
intermittent hypoxemia and sleep fragmentation, with ensuing systemic inflammation …

Key points Intermittent hypoxia leads to long‐lasting increases in muscle sympathetic nerve
activity and blood pressure, contributing to increased risk for hypertension in obstructive …

Key points Ventilatory long‐term facilitation (vLTF) refers to respiratory neuroplasticity that
develops following intermittent hypoxia in both healthy and clinical populations. A sustained …

Animal studies have demonstrated an increase in BP with repeated upper airway closure
and intermittent hypoxia. 25–28 Studies of human subjects have demonstrated increased …

Obstructive sleep apnoea (OSA) is a common disorder and is associated with
cardiovascular disease. Continuous positive airway pressure (CPAP), whilst reducing blood …

Repetitive hypoxic apneas, similar to those observed in sleep apnea, result in resetting of
the sympathetic baroreflex to higher blood pressures (BP). This baroreflex resetting is …

Obstructive sleep apnea (OSA), the most severe form of sleep disordered breathing, is
characterized by intermittent hypoxia during sleep (IH), sleep fragmentation, and episodic …

Background and aims Exposing the endothelium to acute periods of imposed oscillatory
shear stress reduces endothelial function and elevates circulating microparticles (MPs) …

Intermittent (IH), as opposed to continuous hypoxia (CH), is thought to have beneficial effects
on cardiovascular function and health. In the present study, we examined the acute effects of …