Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei

K Billington, C Halliday, R Madden, P Dyer… - Nature …, 2023 - nature.com
Trypanosoma brucei is a model trypanosomatid, an important group of human, animal and
plant unicellular parasites. Understanding their complex cell architecture and life cycle is …

Superspreading drives the COVID pandemic--and could help to tame it.

D Lewis - Nature, 2021 - go.gale.com
Superspreading drives the COVID pandemic -- and could help to tame it. - Document - Gale
Academic OneFile Use this link to get back to this page. Copy Skip to Content Library Menu …

Coordination of the cell cycle in trypanosomes

RJ Wheeler, K Gull, JD Sunter - Annual review of microbiology, 2019 - annualreviews.org
Trypanosomes have complex life cycles within which there are both proliferative and
differentiation cell divisions. The coordination of the cell cycle to achieve these different …

TrypTag. org: from images to discoveries using genome-wide protein localisation in Trypanosoma brucei

JD Sunter, S Dean, RJ Wheeler - Trends in Parasitology, 2023 - cell.com
TrypTag was a 4-year project to tag the N-and C-termini of almost all Trypanosoma brucei
proteins with a fluorescent protein and record the subcellular localisation through images …

FAP106 is an interaction hub for assembling microtubule inner proteins at the cilium inner junction

MM Shimogawa, AS Wijono, H Wang, J Zhang… - Nature …, 2023 - nature.com
Motility of pathogenic protozoa depends on flagella (synonymous with cilia) with axonemes
containing nine doublet microtubules (DMTs) and two singlet microtubules. Microtubule …

Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections

T Beneke, F Demay, E Hookway, N Ashman… - PLoS …, 2019 - journals.plos.org
The protozoan parasite Leishmania possesses a single flagellum, which is remodelled
during the parasite's life cycle from a long motile flagellum in promastigote forms in the sand …

[HTML][HTML] Cellular landmarks of Trypanosoma brucei and Leishmania mexicana

C Halliday, K Billington, Z Wang, R Madden… - Molecular and …, 2019 - Elsevier
The kinetoplastids Trypanosoma brucei and Leishmania mexicana are eukaryotes with a
highly structured cellular organisation that is reproduced with great fidelity in each …

Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines

JM Andrade, LO Gonçalves, DB Liarte, DA Lima… - Parasites & …, 2020 - Springer
Background One of the major challenges to leishmaniasis treatment is the emergence of
parasites resistant to antimony. To study differentially expressed genes associated with drug …

Coordination of eukaryotic cilia and flagella

KY Wan - Essays in biochemistry, 2018 - portlandpress.com
Propulsion by slender cellular appendages called cilia and flagella is an ancient means of
locomotion. Unicellular organisms evolved myriad strategies to propel themselves in fluid …

Assembly of FAP93 at the proximal axoneme in Chlamydomonas cilia

J Hwang, H Yanagisawa, KC Davis, EL Hunter… - …, 2024 - Wiley Online Library
To identify proteins specific to the proximal ciliary axoneme, we used iTRAQ to compare
short (~ 2 μm) and full‐length (~ 11 μm) axonemes of Chlamydomonas. Known compoents …