The human papillomavirus E7 oncoprotein as a regulator of transcription
WK Songock, S Kim, JM Bodily - Virus research, 2017 - Elsevier
High-risk human papillomaviruses (HPVs) encode oncoproteins which manipulate gene
expression patterns in the host keratinocytes to facilitate viral replication, regulate viral …
expression patterns in the host keratinocytes to facilitate viral replication, regulate viral …
Papillomaviruses and endocytic trafficking
A Siddiqa, J Broniarczyk, L Banks - International journal of molecular …, 2018 - mdpi.com
Endocytic trafficking plays a major role in transport of incoming human papillomavirus
(HPVs) from plasma membrane to the trans Golgi network (TGN) and ultimately into the …
(HPVs) from plasma membrane to the trans Golgi network (TGN) and ultimately into the …
In vivo antitumor effect of an intracellular single‐chain antibody fragment against the E7 oncoprotein of human papillomavirus 16
L Accardi, F Paolini, A Mandarino… - … journal of cancer, 2014 - Wiley Online Library
Human papillomavirus (HPV)‐associated tumors still represent an urgent problem of public
health in spite of the efficacy of the prophylactic HPV vaccines. Specific antibodies in single …
health in spite of the efficacy of the prophylactic HPV vaccines. Specific antibodies in single …
Reconstruction of human papillomavirus type 16-mediated early-stage neoplasia implicates E6/E7 deregulation and the loss of contact inhibition in neoplastic …
E Isaacson Wechsler, Q Wang, I Roberts… - Journal of …, 2012 - Am Soc Microbiol
Infection with human papillomavirus type 16 (HPV-16) can lead to low-or high-grade
squamous intraepithelial lesions (LSIL or HSIL). Here we show that these in vivo disease …
squamous intraepithelial lesions (LSIL or HSIL). Here we show that these in vivo disease …
The known and potential intersections of rab-GTPases in human papillomavirus infections
JM Young, A Zine El Abidine… - Frontiers in Cell and …, 2019 - frontiersin.org
Papillomaviruses (PVs) were the first viruses recognized to cause tumors and cancers in
mammalian hosts by Shope, nearly a century ago. Over 40 years ago, first proposed that …
mammalian hosts by Shope, nearly a century ago. Over 40 years ago, first proposed that …
Non-metabolic functions of PKM2 contribute to cervical cancer cell proliferation induced by the HPV16 E7 oncoprotein
Pyruvate kinase M2 (PKM2) mainly catalyzes glycolysis, but it also exerts non-glycolytic
functions in several cancers. While it has been shown to interact with the human …
functions in several cancers. While it has been shown to interact with the human …
The subcellular localisation of the human papillomavirus (HPV) 16 E7 protein in cervical cancer cells and its perturbation by RNA aptamers
Ö Cesur, C Nicol, H Groves, J Mankouri, GE Blair… - Viruses, 2015 - mdpi.com
Human papillomavirus (HPV) is the most common viral infection of the reproductive tract,
affecting both men and women. High-risk oncogenic types are responsible for almost 90% of …
affecting both men and women. High-risk oncogenic types are responsible for almost 90% of …
miR-34a and its novel target, NLRC5, are associated with HPV16 persistence
J Li, L Yu, Z Shen, Y Li, B Chen, W Wei, X Chen… - Infection, Genetics and …, 2016 - Elsevier
Persistent infection with human papillomavirus (HPV), particularly type 16, is causally
associated with cervical cancer and its precursors. The role of miRNAs in HPV16 …
associated with cervical cancer and its precursors. The role of miRNAs in HPV16 …
Proteasomal degradation of p130 facilitate cell cycle deregulation and impairment of cellular differentiation in high-risk Human Papillomavirus 16 and 18 E7 …
Abstract The High-Risk Human Papillomaviruses (HR-HPVs) 16 and 18 are known to cause
cervical cancer, which is primarily attributed to E6 and E7 oncoproteins. In addition, recent …
cervical cancer, which is primarily attributed to E6 and E7 oncoproteins. In addition, recent …
A prime/boost strategy by DNA/fowlpox recombinants expressing a mutant E7 protein for the immunotherapy of HPV-associated cancers
A Radaelli, CDG Morghen, C Zanotto, S Pacchioni… - Virus research, 2012 - Elsevier
Development of effective therapeutic vaccines against human papilloma virus (HPV)
infections remains a priority, considering the high number of new cases of cervical cancer …
infections remains a priority, considering the high number of new cases of cervical cancer …