Monkeypox: disease epidemiology, host immunity and clinical interventions

FM Lum, A Torres-Ruesta, MZ Tay, RTP Lin… - Nature Reviews …, 2022 - nature.com
Monkeypox virus (MPXV), which causes disease in humans, has for many years been
restricted to the African continent, with only a handful of sporadic cases in other parts of the …

Monkeypox and its possible sexual transmission: where are we now with its evidence?

R Sah, A Abdelaal, A Reda, BE Katamesh… - Pathogens, 2022 - mdpi.com
Monkeypox is a rare disease but is increasing in incidence in different countries since the
first case was diagnosed in the UK by the United Kingdom (UK) Health Security Agency on 6 …

[HTML][HTML] Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster …

AM Henao-Restrepo, A Camacho, IM Longini… - The Lancet, 2017 - thelancet.com
Background rVSV-ZEBOV is a recombinant, replication competent vesicular stomatitis virus-
based candidate vaccine expressing a surface glycoprotein of Zaire Ebolavirus. We tested …

Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

AM Henao-Restrepo, IM Longini, M Egger, NE Dean… - The Lancet, 2015 - thelancet.com
Background A recombinant, replication-competent vesicular stomatitis virus-based vaccine
expressing a surface glycoprotein of Zaire Ebolavirus (rVSV-ZEBOV) is a promising Ebola …

[图书][B] Cluster randomised trials

RJ Hayes, LH Moulton - 2017 - taylorfrancis.com
Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of
trials that randomise groups of individuals to different treatments. It explores the advantages …

Outbreak analytics: a developing data science for informing the response to emerging pathogens

JA Polonsky, A Baidjoe, ZN Kamvar… - … of the Royal …, 2019 - royalsocietypublishing.org
Despite continued efforts to improve health systems worldwide, emerging pathogen
epidemics remain a major public health concern. Effective response to such outbreaks relies …

Review of recent methodological developments in group-randomized trials: part 1—design

EL Turner, F Li, JA Gallis… - American journal of …, 2017 - ajph.aphapublications.org
In 2004, Murray et al. reviewed methodological developments in the design and analysis of
group-randomized trials (GRTs). We have highlighted the developments of the past 13 years …

Vaccine waning and mumps re-emergence in the United States

JA Lewnard, YH Grad - Science translational medicine, 2018 - science.org
After decades of declining mumps incidence amid widespread vaccination, the United
States and other developed countries have experienced a resurgence in mumps cases over …

Intradermal SynCon® Ebola GP DNA vaccine is temperature stable and safely demonstrates cellular and humoral immunogenicity advantages in healthy volunteers

P Tebas, KA Kraynyak, A Patel… - The Journal of …, 2019 - academic.oup.com
Background Nonlive vaccine approaches that are simple to deliver and stable at room
temperature or 2–8° C could be advantageous in controlling future Ebola virus (EBOV) …

Safety and immunogenicity of the rVSV∆ G-ZEBOV-GP Ebola virus vaccine candidate in healthy adults: a phase 1b randomised, multicentre, double-blind, placebo …

DG Heppner, TL Kemp, BK Martin… - The Lancet Infectious …, 2017 - thelancet.com
Summary Background The 2014 Zaire Ebola virus outbreak highlighted the need for a safe,
effective vaccine with a rapid onset of protection. We report the safety and immunogenicity of …