Hydrogels prepared via self-assembly offer scalable and tunable platforms for drug delivery
applications. Molecular-scale self-assembly leverages an interplay of attractive and …

Natural tissues and organs exhibit an array of spatial gradients, from the polarized neural
tube during embryonic development to the osteochondral interface present at articulating …

Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Functionally gradient materials (FGM) have gradual variations in their properties along one
or more dimensions due to local compositional or structural distinctions by design …

Articular cartilage is comprised of zones that vary in architecture, extracellular matrix
composition, and mechanical properties. Here, we designed and engineered a porous zonal …

Regenerative medicine strategies for restoring articular cartilage face significant challenges
to recreate the complex and dynamic biochemical and biomechanical functions of native …

The ultimate objective of tissue engineering is to fabricate artificial living constructs with a
structural organization and function that faithfully resembles their native tissue counterparts …

Cardiovascular injuries cause huge morbidity and mortality worldwide. Arterial
reconstructions are generally performed either by using native grafts or synthetic grafts, both …

Concentration gradients are at the basis of many natural phenomena and hold great
importance in human and plant biology. This basic phenomenon has inspired many material …

Nanofiber films produced by electrospinning currently provide a promising platform for
different applications. Although nonfunctionalized nanofiber films from natural or synthetic …