Half a century of biochemical and biophysical experiments has provided attractive models
that may explain the diverse functions of microtubules within cells and organisms. However …

Microtubules are highly dynamic structures, which consist of α-and β-tubulin heterodimers,
and are involved in cell movement, intracellular trafficking, and mitosis. In the context of …

Microtubules are key cytoskeletal elements of all eukaryotic cells and are assembled of
evolutionarily conserved α-tubulin–β-tubulin heterodimers. Despite their uniform structure …

Chromosome congression during prometaphase culminates with the establishment of a
metaphase plate, a hallmark of mitosis in metazoans. Classical views resulting from more …

All microtubules are built from a basic α/β-tubulin building block, yet subpopulations of
microtubules can be differentially marked by a number of post-translational modifications …

Parthenolide, a naturally occurring sesquiterpene lactone derived from feverfew (Tanacetum
parthenium), exhibits exceptional anti-cancer and anti-inflammatory properties, making it a …

Cellular microtubules are marked by abundant and evolutionarily conserved post‐
translational modifications that have the potential to tune their functions. This review focuses …

The “tubulin code” combines different α/β-tubulin isotypes with several post-translational
modifications (PTMs) to generate microtubule diversity in cells. During cell division, specific …

Compounds targeting microtubules are widely used in cancer therapy with a proven efficacy.
However, because they also target non-cancerous cells, their administration leads to …

Microtubules (MTs), highly dynamic structures composed of α-and β-tubulin heterodimers,
are involved in cell movement and intracellular traffic and are essential for cell division …