From progenitors to progeny: shaping striatal circuit development and function
R Knowles, N Dehorter, T Ellender - Journal of Neuroscience, 2021 - Soc Neuroscience
Understanding how neurons of the striatum are formed and integrate into complex synaptic
circuits is essential to provide insight into striatal function in health and disease. In this …
circuits is essential to provide insight into striatal function in health and disease. In this …
Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior
LP Fang, N Zhao, LC Caudal, HF Chang… - Nature …, 2022 - nature.com
Cortical neural circuits are complex but very precise networks of balanced excitation and
inhibition. Yet, the molecular and cellular mechanisms that form the balance are just …
inhibition. Yet, the molecular and cellular mechanisms that form the balance are just …
CUT homeobox genes: transcriptional regulation of neuronal specification and beyond
E Leyva-Díaz - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
CUT homeobox genes represent a captivating gene class fulfilling critical functions in the
development and maintenance of multiple cell types across a wide range of organisms …
development and maintenance of multiple cell types across a wide range of organisms …
Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior
The innate immune system shapes brain development and is implicated in
neurodevelopmental diseases. It is critical to define the relevant immune cells and signals …
neurodevelopmental diseases. It is critical to define the relevant immune cells and signals …
Interneuron Diversity: How Form Becomes Function
NVDM García, G Fishell - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
A persistent question in neuroscience is how early neuronal subtype identity is established
during the development of neuronal circuits. Despite significant progress in the …
during the development of neuronal circuits. Despite significant progress in the …
Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers
S Venkataramanappa, F Saaber, P Abe, D Schütz… - Cell Reports, 2022 - cell.com
The function of the cerebral cortex depends on various types of interneurons (cortical
interneurons [cINs]) and their appropriate allocation to the cortical layers. Caudal ganglionic …
interneurons [cINs]) and their appropriate allocation to the cortical layers. Caudal ganglionic …
Interferon-γ augments GABA release in the developing neocortex via nitric oxide synthase/soluble guanylate cyclase and constrains network activity
N Döhne, A Falck, GMS Janach, E Byvaltcev… - Frontiers in cellular …, 2022 - frontiersin.org
Interferon-γ (IFN-γ), a cytokine with neuromodulatory properties, has been shown to
enhance inhibitory transmission. Because early inhibitory neurotransmission sculpts …
enhance inhibitory transmission. Because early inhibitory neurotransmission sculpts …
Developmental brain asymmetry. The good and the bad sides
Brain asymmetry is a hallmark of the human brain. Recent studies report a certain degree of
abnormal asymmetry of brain lateralization between left and right brain hemispheres can be …
abnormal asymmetry of brain lateralization between left and right brain hemispheres can be …
Neurophysiology of the developing cerebral cortex: What we have learned and what we need to know
HJ Luhmann - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
This review article aims to give a brief summary on the novel technologies, the challenges,
our current understanding, and the open questions in the field of the neurophysiology of the …
our current understanding, and the open questions in the field of the neurophysiology of the …
Developmental synapse pathology triggered by maternal exposure to the herbicide glufosinate ammonium
H Izumi, M Demura, A Imai, R Ogawa… - Frontiers in Molecular …, 2023 - frontiersin.org
Environmental and genetic factors influence synapse formation. Numerous animal
experiments have revealed that pesticides, including herbicides, can disturb normal …
experiments have revealed that pesticides, including herbicides, can disturb normal …