Transglutaminase regulation of cell function

RL Eckert, MT Kaartinen, M Nurminskaya… - Physiological …, 2014 - journals.physiology.org
Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

BH3-only proteins in apoptosis and beyond: an overview

E Lomonosova, G Chinnadurai - Oncogene, 2008 - nature.com
Abstract BH3-only BCL-2 family proteins are effectors of canonical mitochondrial apoptosis.
They discharge their pro-apoptotic functions through BH1–3 pro-apoptotic proteins such as …

Cellular functions of tissue transglutaminase

MV Nurminskaya, AM Belkin - International review of cell and molecular …, 2012 - Elsevier
Transglutaminase 2 (TG2 or tissue transglutaminase) is a highly complex multifunctional
protein that acts as transglutaminase, GTPase/ATPase, protein disulfide isomerase, and …

[HTML][HTML] Transglutaminase 2: a molecular Swiss army knife

S Gundemir, G Colak, J Tucholski… - Biochimica et Biophysica …, 2012 - Elsevier
Transglutaminase 2 (TG2) is the most widely distributed member of the transglutaminase
family with almost all cell types in the body expressing TG2 to varying extents. In addition to …

[HTML][HTML] Role of transglutaminase 2 in cell death, survival, and fibrosis

H Tatsukawa, K Hitomi - Cells, 2021 - mdpi.com
Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme catalyzing the crosslinking
between Gln and Lys residues and involved in various pathophysiological events. Besides …

Tissue transglutaminase: A multifunctional and multisite regulator in health and disease

Z Yao, Y Fan, L Lin, RE Kellems… - Physiological …, 2024 - journals.physiology.org
Tissue transglutaminase (TG2) is a widely distributed multifunctional protein involved in a
broad range of cellular and metabolic functions carried out in a variety of cellular …

[HTML][HTML] Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death

H Tatsukawa, Y Furutani, K Hitomi, S Kojima - Cell death & disease, 2016 - nature.com
Abstract Transglutaminase 2 (TG2) is primarily known as the most ubiquitously expressed
member of the transglutaminase family with Ca 2+-dependent protein crosslinking activity; …

[HTML][HTML] Transglutaminase 2 in the balance of cell death and survival

L Fésüs, Z Szondy - FEBS letters, 2005 - Elsevier
Transglutaminase 2 (TG2), a multifunctional enzyme with Ca2+-dependent protein
crosslinking activity and GTP-dependent G protein functions, is often upregulated in cells …

Transglutaminase 2: a multi-functional protein in multiple subcellular compartments

D Park, SS Choi, KS Ha - Amino acids, 2010 - Springer
Abstract Transglutaminase 2 (TG2) is a multifunctional protein that can function as a
transglutaminase, G protein, kinase, protein disulfide isomerase, and as an adaptor protein …

BH 3‐only proteins: a 20‐year stock‐take

M Doerflinger, JA Glab, H Puthalakath - The FEBS journal, 2015 - Wiley Online Library
BH 3‐only proteins are the sentinels of cellular stress, and their activation commits cells to
apoptosis. Since the discovery of the first BH 3‐only protein BAD almost 20 years ago, at …