Dynamics of ACTH and cortisol secretion and implications for disease
SL Lightman, MT Birnie… - Endocrine …, 2020 - academic.oup.com
The past decade has seen several critical advances in our understanding of hypothalamic–
pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate …
pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate …
[HTML][HTML] Regulation of the hypothalamic-pituitary-adrenocortical stress response
JP Herman, JM McKlveen, S Ghosal… - Comprehensive …, 2016 - ncbi.nlm.nih.gov
The hypothalamo-pituitary-adrenocortical (HPA axis) is required for stress adaptation.
Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ …
Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ …
Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility
JK Gjerstad, SL Lightman, F Spiga - Stress, 2018 - Taylor & Francis
The hypothalamic–pituitary–adrenal (HPA) axis is the major neuroendocrine axis regulating
homeostasis in mammals. Glucocorticoid hormones are rapidly synthesized and secreted …
homeostasis in mammals. Glucocorticoid hormones are rapidly synthesized and secreted …
Sex differences in the hypothalamic–pituitary–adrenal axis' response to stress: an important role for gonadal hormones
AL Heck, RJ Handa - Neuropsychopharmacology, 2019 - nature.com
The hypothalamic–pituitary–adrenal (HPA) axis, a neuroendocrine network that controls
hormonal responses to internal and external challenges in an organism's environment …
hormonal responses to internal and external challenges in an organism's environment …
[HTML][HTML] Cannabidiol as a potential treatment for anxiety disorders
EM Blessing, MM Steenkamp, J Manzanares… - …, 2015 - Elsevier
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum
drug that in recent years has drawn increasing interest as a treatment for a range of …
drug that in recent years has drawn increasing interest as a treatment for a range of …
Stress, glucocorticoids and memory: implications for treating fear-related disorders
D de Quervain, L Schwabe… - Nature Reviews …, 2017 - nature.com
Glucocorticoid stress hormones are crucially involved in modulating mnemonic processing
of emotionally arousing experiences. They enhance the consolidation of new memories …
of emotionally arousing experiences. They enhance the consolidation of new memories …
Neurobiological interactions between stress and the endocannabinoid system
Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …
many neurobehavioral processes. A growing body of work indicates that the …
The endocannabinoid system in guarding against fear, anxiety and stress
The endocannabinoid (eCB) system has emerged as a central integrator linking the
perception of external and internal stimuli to distinct neurophysiological and behavioural …
perception of external and internal stimuli to distinct neurophysiological and behavioural …
Hormonal treatments for major depressive disorder: state of the art
Major depressive disorder is a common psychiatric disorder associated with marked
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …
Cannabidiol (CBD) use in psychiatric disorders: A systematic review
S Bonaccorso, A Ricciardi, C Zangani, S Chiappini… - Neurotoxicology, 2019 - Elsevier
Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …