Mitochondrial dysfunction and oxidative stress caused by cryopreservation in reproductive cells

R Gualtieri, G Kalthur, V Barbato, M Di Nardo, SK Adiga… - Antioxidants, 2021 - mdpi.com
Mitochondria, fundamental organelles in cell metabolism, and ATP synthesis are
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …

Free radicals: their beneficial and detrimental effects on sperm function

S Kothari, A Thompson, A Agarwal, SS du Plessis - 2010 - nopr.niscpr.res.in
Free radicals are molecules with one or more unpaired electron (s) commonly found in
seminal plasma. Physiologically, free radicals control sperm maturation, capacitation and …

Reactive nitrogen species and male reproduction: Physiological and pathological aspects

S Dutta, P Sengupta, S Das, P Slama… - International Journal of …, 2022 - mdpi.com
Reactive nitrogen species (RNS), like reactive oxygen species (ROS), are useful for
sustaining reproductive processes such as cell signaling, the regulation of hormonal …

Impact of oxidative stress on male fertility—A review

E Tvrdá, Z Kňažická, L Bárdos, P Massányi… - Acta veterinaria …, 2011 - akjournals.com
Oxidative stress is a state related to increased cellular damage caused by oxygen and
oxygen-derived free radicals known as reactive oxygen species (ROS). It is a serious …

Unexplained male infertility: potential causes and management

A Hamada, SC Esteves, A Agarwal - Human Andrology, 2011 - journals.lww.com
Unexplained male infertility: potential causes and managemen... : Human Andrology
Unexplained male infertility: potential causes and management : Human Andrology Log in or …

Toxic effect of cyclophosphamide on sperm morphology, testicular histology and blood oxidant‐antioxidant balance, and protective roles of lycopene and ellagic acid

AO Çeribaşi, G Türk, M Sönmez… - Basic & Clinical …, 2010 - Wiley Online Library
In this study, the toxic effect of cyclophosphamide (CP) on sperm morphology, testicular
histology and blood oxidant–antioxidant balance, and protective roles of lycopene (LC) and …

Free radical and superoxide reactivity detection in semen quality assessment: past, present, and future

J Gosalvez, E Tvrda, A Agarwal - Journal of assisted reproduction and …, 2017 - Springer
Oxidative stress is a well-established cause of male infertility, with reactive oxygen species
(ROS) impairing sperm production, motility, membrane, and DNA integrity. Currently, most …

Proteomic analysis of human spermatozoa proteins with oxidative stress

R Sharma, A Agarwal, G Mohanty, AJ Hamada… - Reproductive Biology …, 2013 - Springer
Background Oxidative stress plays a key role in the etiology of male infertility. Significant
alterations in the sperm proteome are associated with poor semen quality. The aim of the …

Antiperoxidative and anti-apoptotic effects of lycopene and ellagic acid on cyclophosphamide-induced testicular lipid peroxidation and apoptosis

G Türk, AO Çeribaşi, F Sakin, M Sönmez… - Reproduction, fertility …, 2010 - CSIRO Publishing
The present study was conducted to investigate the possible protective effects of lycopene
(LC) and ellagic acid (EA) on cyclophosphamide (CP)-induced testicular and spermatozoal …

Impact of ellagic acid on adriamycin-induced testicular histopathological lesions, apoptosis, lipid peroxidation and sperm damages

AO Çeribaşı, F Sakin, G Türk, M Sönmez… - … and toxicologic pathology, 2012 - Elsevier
The aim of the present study was to investigate whether ellagic acid (EA) has protective
effect on adriamycin (ADR)-induced testicular and spermatozoal toxicity associated with the …