Cyclic peptides are molecules that are already used as drugs in therapies approved for
various pharmacological activities, for example, as antibiotics, antifungals, anticancer, and …

Over the last decade, the management of acute respiratory distress syndrome (ARDS) has
made considerable progress both regarding supportive and pharmacologic therapies. Lung …

Epithelial sodium channels (ENaC) are part of a complex network of interacting biochemical
pathways and as such are involved in several disease states. Dependent on site and type of …

Alveolar-capillary leak is a hallmark of the acute respiratory distress syndrome (ARDS), a
potentially lethal complication of severe sepsis, trauma and pneumonia, including COVID …

Background This systematic review evaluates pneumolysin (PLY) as a target for new
treatments against pneumococcal infections. Pneumolysin is one of the main virulence …

ABSTRACT Introduction Acute Respiratory Distress Syndrome (ARDS) is a heterogeneous
form of lung injury with severe hypoxemia and bilateral infiltrates after an inciting event that …

In the pharmaceutical industry, it is essential to ensure the safety and efficacy of medicinal
products. Therefore a robust quality assurance framework is needed. This manuscript …

Introduction Ventilatory management and general supportive care of acute respiratory
distress syndrome (ARDS) in the adult population have led to significant clinical …

Introduction Acute respiratory distress syndrome (ARDS) is characterized by acute
inflammatory injury to the lungs, alterations in vascular permeability, loss of aerated tissue …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has swept the whole world
and brought about a public health crisis of unprecedented proportions. To combat the rapid …