Amyloid-β (Aβ) accumulation is one of the cardinal pathological hallmarks of Alzheimer's
disease and plays an important role in its pathogenesis. Although the neurotoxic effects of …

Alzheimer's disease as the most common age-related dementia affects more than 40 million
people in the world, representing a global public health priority. However, the pathogenesis …

Post-traumatic stress disorder (PTSD) represents a global public health concern, affecting
about 1 in 20 individuals. The symptoms of PTSD include intrusiveness (involuntary …

Purpose To test the hypothesis that periodontitis is associated with AD and search whether
periodontal and other variables would negatively impact the oral health-related quality of life …

Aims The objectives of this work were to assess the possibility of administration of
omarigliptin and/or galangin to combat lipopolysaccharide (LPS)-induced …

Amyloid-β (Aβ) accumulation is one of the main pathological hallmarks of Alzheimer's
disease (AD). Porphyromonas gingivalis (P. gingivalis), the pathogen of chronic …

Background The relationship between periodontitis and Alzheimer's disease (AD) has
attracted more attention recently, whereas profiles of subgingival microbiomes and gingival …

The development of non-invasive brain-targeting delivery approaches is very important for
the treatment of diseases related to the central nervous system (CNS), and receptor …

Background: In patients with Alzheimer's disease (AD), bacterial infections are often
associated with a cognitive decline. Animal models of genuine acute infections with viable …

The rise of multidrug-resistant pathogens has awakened interest in new drug candidates
such as antimicrobial peptides and their derivatives. Recent work suggests that some …