Tackling drug resistance and other causes of treatment failure in leishmaniasis

GJ Wijnant, F Dumetz, L Dirkx, D Bulté… - Frontiers in Tropical …, 2022 - frontiersin.org
Leishmaniasis is a tropical infectious disease caused by the protozoan Leishmania parasite.
The disease is transmitted by female sand flies and, depending on the infecting parasite …

Involvement of Leishmania Phosphatases in Parasite Biology and Pathogeny

AL Freitas-Mesquita, ALA Dos-Santos… - Frontiers in Cellular …, 2021 - frontiersin.org
In the Leishmania lifecycle, the motile promastigote form is transmitted from the sand fly
vector to a mammalian host during a blood meal. Inside vertebrate host macrophages, the …

In vitro miltefosine and amphotericin B susceptibility of strains and clinical isolates of Leishmania species endemic in Brazil that cause tegumentary leishmaniasis

BA Ferreira, EM Coser, C Saborito… - Experimental …, 2023 - Elsevier
Tegumentary leishmaniasis encompasses a spectrum of clinical manifestations caused by
the parasitic protozoa of the genus Leishmania. In Brazil, there are at least seven …

Full nucleotide sequencing of ribosomal DNA internal transcribed spacer of Leishmania species causing cutaneous leishmaniasis in Brazil and its potential for …

CR Espada, BA Ferreira, PA Ortiz, SRB Uliana… - Acta Tropica, 2021 - Elsevier
Species-specific diagnosis still represents a challenge in leishmaniasis management,
particularly in regions with multiple endemic species. In Brazil, seven species have been …

Leishmania major Infection in Synanthropic Rodents: Evidence for the Urbanization of Zoonotic Cutaneous Leishmaniasis (ZCL) in Southern Iran

S Shahabi, K Azizi, Q Asgari… - Canadian Journal of …, 2024 - Wiley Online Library
Cutaneous leishmaniasis is of particular importance in southern Iran. This study aimed to
investigate the infection of rodents with Leishmania major in an urban area of Fars Province …

Isolation, typing, and drug susceptibility of Leishmania (Leishmania) infantum isolates from dogs of the municipality of Embu das Artes, an endemic region for canine …

BA Ferreira, TFC Martins, EM Coser… - Parasitology …, 2022 - Springer
Abstract The parasitic protozoa Leishmania (Leishmania) infantum is the etiological agent of
human visceral leishmaniasis and canine leishmaniasis in South America, where Brazil is …

Polyamine and trypanothione pathways as targets for novel antileishmanial drugs

IA Rodrigues, AR Garcia, MM Paz… - … Drug Development and …, 2021 - Springer
Leishmaniasis is an infectious disease classified by WHO as one of the neglected tropical
diseases. Due to the lack of human vaccines, chemotherapeutic agents represent the only …

[PDF][PDF] Identificação e validação funcional de genes associados à suscetibilidade e resistência à paromomicina em Leishmania spp.

EM Coser - 2024 - repositorio.unicamp.br
1.10 Mecanismos de resistência aos fármacos em Leishmania............................... 2.
Justificativa.............................................................................................................. 3 …

Involvement of Leishmania Phosphatases in Parasite Biology and Pathogeny

JD Ramırez - Advances in the Molecular Biology of …, 2021 - books.google.com
Leishmania spp. are trypanosomatid parasites that infect humans and other mammals
(Chang, 1983). Leishmaniasis may be asymptomatic or it may manifest as cutaneous or …

[PDF][PDF] INVESTIGAÇÃO DO PAPEL DAS PROTEÍNAS ABC (SUBFAMÍLIA F) NA RESISTÊNCIA À PAROMOMICINA EM LEISHMANIA AMAZONENSIS

TR COSTA - repositorio.unicamp.br
A leishmaniose é uma doença parasitária com ampla distribuição geográfica no Brasil e no
mundo, ocorrendo principalmente em áreas tropicais e subtropicais. Esta parasitose é …