[HTML][HTML] Revolutionizing Heart Transplantation: A Multidisciplinary Approach to Xenotransplantation, Immunosuppression, Regenerative Medicine, Artificial …

Y Tanveer, A Arif, T Tsenteradze, NN Anika, D Bakht… - Cureus, 2023 - ncbi.nlm.nih.gov
Heart transplantation (HTx) stands as a life-saving intervention for patients with end-stage
heart disease, but the field is fraught with numerous challenges that span from the scarcity of …

[HTML][HTML] Editing the Human Genome with CRISPR/Cas: A Review of its Molecular Basis, Current Clinical Applications, and Bioethical Implications

M Ahumada-Ayala, R Aguilar-López… - Revista de …, 2023 - scielo.org.mx
ABSTRACT CRISPR/Cas genes evolved in prokaryotic organisms as a mechanism of
defense designed to identify and destroy genetic material from threatening viruses. A …

A scalable corneal xenograft platform: simultaneous opportunities for tissue engineering and circular economic sustainability by repurposing slaughterhouse waste

X Wang, A Shakeel, AE Salih, H Vurivi… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: Corneal disease is a leading cause of blindness globally that stems from
various etiologies. High-throughput platforms that can generate substantial quantities of …

Research prospects for kidney xenotransplantation: a bibliometric analysis

S Yang, M Zhang, H Wei, B Zhang, J Peng, P Shang… - Renal …, 2024 - Taylor & Francis
Background Xenograft kidney transplantation has been receiving increasing attention. The
purpose of this study is to use bibliometric analysis to identify papers in this research field …

In defense of xenotransplantation research: Because of, not in spite of, animal welfare concerns

C Bobier, D Rodger, DJ Hurst… - …, 2023 - Wiley Online Library
It is envisioned that one day xenotransplantation will bring about a future where
transplantable organs can be safely and efficiently grown in transgenic pigs to help meet the …

Gene-edited pigs: a translational model for human food allergy against alpha-Gal and anaphylaxis

Y Wang, M Hils, A Fischer, F Wölbing… - Frontiers in …, 2024 - frontiersin.org
The prevalence of food allergy is rising and is estimated to approach 10%. Red meat allergy
is the first known food allergy elicited by immunoglobulin E (IgE) antibodies recognizing a …

Xenotransplantation clinical trials and equitable patient selection

C Bobier, D Rodger - Cambridge Quarterly of Healthcare Ethics, 2024 - cambridge.org
Xenotransplant patient selection recommendations restrict clinical trial participation to
seriously ill patients for whom alternative therapies are unavailable or who will likely die …

Moral approval of xenotransplantation in Egypt: associations with religion, attitudes towards animals and demographic factors

G Andrade, E AboHamza, Y Elsantil, AE Ayoub… - BMC Medical …, 2024 - Springer
Xenotransplantation has great potential as an alternative to alleviate the shortage of organs
for donation. However, given that the animal most suited for xenotransplantation is the pig …

Analysis of PERV-C superinfection resistance using HA-tagged viruses

M Flecks, N Fischer, J Krijnse Locker, RR Tönjes… - Retrovirology, 2023 - Springer
Background Using pigs as organ donors has advanced xenotransplantation to the point that
it is almost ready for clinical use. However, there is still a zoonotic risk associated with …

40 years of AETE: the contribution of scientists and practitioners to the progress of reproductive biotechnologies in Europe

C Galli, G Lazzari - Animal Reproduction, 2024 - SciELO Brasil
This conference celebrates the 40th anniversary of AETE. Over the past 40 years, AETE has
served as a forum for scientists, practitioners, and students working in assisted animal …