Translating biosynthetic gene clusters into fungal armor and weaponry

NP Keller - Nature chemical biology, 2015 - nature.com
Filamentous fungi are renowned for the production of a diverse array of secondary
metabolites (SMs) where the genetic material required for synthesis of a SM is typically …

Regulation of Conidiogenesis in Aspergillus flavus

HJ Cho, SH Son, W Chen, YE Son, I Lee, JH Yu… - Cells, 2022 - mdpi.com
Aspergillus flavus is a representative fungal species in the Aspergillus section Flavi and has
been used as a model system to gain insights into fungal development and toxin production …

Central role of the trehalose biosynthesis pathway in the pathogenesis of human fungal infections: opportunities and challenges for therapeutic development

A Thammahong, S Puttikamonkul… - Microbiology and …, 2017 - Am Soc Microbiol
Invasive fungal infections cause significant morbidity and mortality in part due to a limited
antifungal drug arsenal. One therapeutic challenge faced by clinicians is the significant host …

Antioxidants Potential of the Filamentous Fungi (Mucor circinelloides)

A Hameed, SA Hussain, J Yang, MU Ijaz, Q Liu… - Nutrients, 2017 - mdpi.com
Three important strains of Mucor circinelloides grown in complete and minimal media for
specified period (72 h, 120 h and 168 h) under submerged fermentation conditions were …

Bioactive components of pomegranate oil and their influence on mycotoxin secretion

AN Badr, HS Ali, AG Abdel-Razek, MG Shehata… - Toxins, 2020 - mdpi.com
Pomegranate, similar to other fruits, has juice-extraction by-products. Pomegranate seed oil
(PGO) is a non-traditional oil with health benefits, rich in bioactive components. This study …

[HTML][HTML] In-host microevolution of Aspergillus fumigatus: A phenotypic and genotypic analysis

E Ballard, WJG Melchers, J Zoll, AJP Brown… - Fungal Genetics and …, 2018 - Elsevier
In order to survive, Aspergillus fumigatus must adapt to specific niche environments.
Adaptation to the human host includes modifications facilitating persistent colonisation and …

The impact of bZIP Atf1ortholog global regulators in fungi

É Leiter, T Emri, K Pákozdi, L Hornok, I Pócsi - Applied Microbiology and …, 2021 - Springer
Regulation of signal transduction pathways is crucial for the maintenance of cellular
homeostasis and organismal development in fungi. Transcription factors are key elements of …

Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion

V Kurucz, T Krüger, K Antal, AM Dietl, H Haas, I Pócsi… - BMC genomics, 2018 - Springer
Background Aspergillus fumigatus has to cope with a combination of several stress types
while colonizing the human body. A functional interplay between these different stress …

bZIP transcription factors PcYap1 and PcRsmA link oxidative stress response to secondary metabolism and development in Penicillium chrysogenum

WD Pérez-Pérez, U Carrasco-Navarro… - Microbial Cell …, 2022 - Springer
Background Reactive oxygen species (ROS) trigger different morphogenic processes in
filamentous fungi and have been shown to play a role in the regulation of the biosynthesis of …

FvatfA regulates growth, stress tolerance as well as mycotoxin and pigment productions in Fusarium verticillioides

Z Szabó, K Pákozdi, K Murvai, T Pusztahelyi… - Applied Microbiology …, 2020 - Springer
FvatfA from the maize pathogen Fusarium verticillioides putatively encodes the Aspergillus
nidulans AtfA and Schizasaccharomyces pombe Atf1 orthologous bZIP-type transcription …