Knowledge of the molecular genetic basis of resistance to antituberculous agents has
advanced rapidly since we reviewed this topic 3 years ago. Virtually all isolates resistant to …

Infections have been the major cause of disease throughout the history of human
populations. With the introduction of antibiotics, it was thought that this problem should …

Tuberculosis (TB) affects humans and other animals and is caused by bacteria from the
Mycobacterium tuberculosis complex (MTBC). Previous studies have shown that there are at …

Mycobacterium bovis and closely associated acid-fast bacilli cause disease in humans.
Epidemiologic investigations reveal that the organism may be ingested or inhaled. Extra …

van Soolingen D (National Institute of Public Health and the Environment, Bilthoven, The
Netherlands). Molecular epidemiology of tuberculosis and other mycobacterial infections …

The direct repeat region in Mycobacterium tuberculosis complex strains is composed of
multiple direct variant repeats (DVRs), each of which is composed of a 36-bp direct repeat …

Isolates from the Mycobacterium tuberculosis complex cultured from caprine pathological
tissue samples were biochemically and genetically characterized. The isolates were …

In a previous report, we described a PCR protocol for the differentiation of the various
species of the Mycobacterium tuberculosis complex (MTC) on the basis of genomic …

Contrary to what was thought previously, bacteria seem to be, not merely spectators to their
own evolution, but, through a variety of mechanisms, able to increase the rate at which …

Tuberculosis continues to be an important disease both in humans and animals. It causes
morbidity, mortality, and economic loss worldwide. The occurrence of Mycobacterium bovis …