Piecing together the patchwork of contact sites
Contact sites are places where two organelles join together to carry out a shared activity
requiring nonvesicular communication. A large number of contact sites have been …
requiring nonvesicular communication. A large number of contact sites have been …
Making sense of eukaryotic DNA replication origins
DM Gilbert - Science, 2001 - science.org
DNA replication is the process by which cells make one complete copy of their genetic
information before cell division. In bacteria, readily identifiable DNA sequences constitute …
information before cell division. In bacteria, readily identifiable DNA sequences constitute …
[图书][B] Molecular modeling and simulation: an interdisciplinary guide
T Schlick - 2010 - Springer
Science is a way of looking, reverencing. And the purpose of all science, like living, which
amounts to the same thing, is not the ac cumulation of gnostic power, the fixing of formulas …
amounts to the same thing, is not the ac cumulation of gnostic power, the fixing of formulas …
Protein structure prediction and structural genomics
Genome sequencing projects are producing linear amino acid sequences, but full
understanding of the biological role of these proteins will require knowledge of their …
understanding of the biological role of these proteins will require knowledge of their …
A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport
Sterol traffic between the endoplasmic reticulum (ER) and plasma membrane (PM) is a
fundamental cellular process that occurs by a poorly understood non-vesicular mechanism …
fundamental cellular process that occurs by a poorly understood non-vesicular mechanism …
Distance‐scaled, finite ideal‐gas reference state improves structure‐derived potentials of mean force for structure selection and stability prediction
The distance‐dependent structure‐derived potentials developed so far all employed a
reference state that can be characterized as a residue (atom)‐averaged state. Here, we …
reference state that can be characterized as a residue (atom)‐averaged state. Here, we …
Principal component analysis for protein folding dynamics
GG Maisuradze, A Liwo, HA Scheraga - Journal of molecular biology, 2009 - Elsevier
Protein folding is considered here by studying the dynamics of the folding of the triple β-
strand WW domain from the Formin-binding protein 28. Starting from the unfolded state and …
strand WW domain from the Formin-binding protein 28. Starting from the unfolded state and …
SPICKER: A clustering approach to identify near‐native protein folds
Y Zhang, J Skolnick - Journal of computational chemistry, 2004 - Wiley Online Library
We have developed SPICKER, a simple and efficient strategy to identify near‐native folds by
clustering protein structures generated during computer simulations. In general, the most …
clustering protein structures generated during computer simulations. In general, the most …
Statistical potentials for fold assessment
A protein structure model generally needs to be evaluated to assess whether or not it has
the correct fold. To improve fold assessment, four types of a residue‐level statistical potential …
the correct fold. To improve fold assessment, four types of a residue‐level statistical potential …