Piecing together the patchwork of contact sites

AT Gatta, TP Levine - Trends in cell biology, 2017 - cell.com
Contact sites are places where two organelles join together to carry out a shared activity
requiring nonvesicular communication. A large number of contact sites have been …

Making sense of eukaryotic DNA replication origins

DM Gilbert - Science, 2001 - science.org
DNA replication is the process by which cells make one complete copy of their genetic
information before cell division. In bacteria, readily identifiable DNA sequences constitute …

[图书][B] Molecular modeling and simulation: an interdisciplinary guide

T Schlick - 2010 - Springer
Science is a way of looking, reverencing. And the purpose of all science, like living, which
amounts to the same thing, is not the ac cumulation of gnostic power, the fixing of formulas …

Protein structure prediction and structural genomics

D Baker, A Sali - Science, 2001 - science.org
Genome sequencing projects are producing linear amino acid sequences, but full
understanding of the biological role of these proteins will require knowledge of their …

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

AT Gatta, LH Wong, YY Sere, DM Calderon-Norena… - elife, 2015 - elifesciences.org
Sterol traffic between the endoplasmic reticulum (ER) and plasma membrane (PM) is a
fundamental cellular process that occurs by a poorly understood non-vesicular mechanism …

Distance‐scaled, finite ideal‐gas reference state improves structure‐derived potentials of mean force for structure selection and stability prediction

H Zhou, Y Zhou - Protein science, 2002 - Wiley Online Library
The distance‐dependent structure‐derived potentials developed so far all employed a
reference state that can be characterized as a residue (atom)‐averaged state. Here, we …

Principal component analysis for protein folding dynamics

GG Maisuradze, A Liwo, HA Scheraga - Journal of molecular biology, 2009 - Elsevier
Protein folding is considered here by studying the dynamics of the folding of the triple β-
strand WW domain from the Formin-binding protein 28. Starting from the unfolded state and …

SPICKER: A clustering approach to identify near‐native protein folds

Y Zhang, J Skolnick - Journal of computational chemistry, 2004 - Wiley Online Library
We have developed SPICKER, a simple and efficient strategy to identify near‐native folds by
clustering protein structures generated during computer simulations. In general, the most …

[图书][B] Spin glasses and complexity

DL Stein, CM Newman - 2013 - books.google.com
Spin glasses are disordered magnetic systems that have led to the development of
mathematical tools with an array of real-world applications, from airline scheduling to neural …

Statistical potentials for fold assessment

F Melo, R Sánchez, A Sali - Protein science, 2002 - Wiley Online Library
A protein structure model generally needs to be evaluated to assess whether or not it has
the correct fold. To improve fold assessment, four types of a residue‐level statistical potential …