Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of
inadequate drug dissolution rates, is one of the most significant challenges that …

Science and technology have always been the vitals of human's struggle, utilized
exclusively for the development of novel tools and products, ranging from micro-to nanosize …

Hot-melt extrusion (HME) technology is one of the primary approaches that has been
implemented in recent years to overcome poor drug solubility/dissolution issues through the …

Nanomedicine consists of the application of nanotechnologies in the medical field. In many
nanomedical applications, supercritical fluids based processes represent the best potential …

Many active ingredients currently prescribed show limited therapeutic efficacy, mainly due to
their dissolution rate inadequate to treat the pathology of interest. A large drug particle size …

Nanosized natural polymers have attained considerable attention in drug delivery
applications due to their high encapsulation efficiency, non-toxic nature, sustained and …

Polymeric nanoparticles have the potential to overcome the barriers associated with oral
drug delivery to protect the drug from the harsh gastric conditions and provide controlled …

We have developed a nano drug delivery system for the treatment of tuberculosis (TB) using
rifampicin (RF) encapsulated in poly (ester amide) s nanoparticles (PEA-RF-NPs), which are …

In this study, the preparation of an inclusion complex of baicalein (BAI) and hydroxypropyl-β-
cyclodextrin (HP-β-CD) using the precipitation with compressed antisolvents (PCA) process …

Herein we report the formation of dry powder complexes of ibuprofen (IBU) and
hydroxypropyl-γ-cyclodextrin (HP-γ-CyD) by supercritical CO 2-assisted spray-drying …