The blood–brain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal transduction and …, 2023 - nature.com
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

[HTML][HTML] Nanocarrier-based drug combination therapy for glioblastoma

M Zhao, D van Straten, MLD Broekman, V Préat… - Theranostics, 2020 - ncbi.nlm.nih.gov
The current achievements in treating glioblastoma (GBM) patients are not sufficient because
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …

[HTML][HTML] Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain

LL Israel, A Galstyan, E Holler, JY Ljubimova - Journal of Controlled …, 2020 - Elsevier
Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …

Tailor made magnetic nanolights: Fabrication to cancer theranostics applications

P Das, S Ganguly, S Margel, A Gedanken - Nanoscale Advances, 2021 - pubs.rsc.org
Nanoparticles having magnetic and fluorescent properties could be considered as a gift to
materials scientists due to their unique magneto-optical qualities. Multiple component …

Two‐Pronged Intracellular Co‐Delivery of Antigen and Adjuvant for Synergistic Cancer Immunotherapy

J Meng, P Zhang, Q Chen, Z Wang, Y Gu… - Advanced …, 2022 - Wiley Online Library
Nanovaccines have emerged as promising alternatives or complements to conventional
cancer treatments. Despite the progresses, specific co‐delivery of antigen and adjuvant to …

Liposomes containing nanoparticles: preparation and applications

V De Leo, AM Maurelli, L Giotta, L Catucci - Colloids and Surfaces B …, 2022 - Elsevier
The impetuous development of nanotechnology over the past two decades has enabled the
production of a plethora of nanomaterials with outstanding optical, magnetic, electrical …

Hybrid nanosystems for biomedical applications

J Seaberg, H Montazerian, MN Hossen… - ACS …, 2021 - ACS Publications
Inorganic/organic hybrid nanosystems have been increasingly developed for their versatility
and efficacy at overcoming obstacles not readily surmounted by nonhybridized counterparts …

Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy

C Wang, W Fan, Z Zhang, Y Wen, L Xiong… - Advanced …, 2019 - Wiley Online Library
Surgical resection is the primary and most effective treatment for most patients with solid
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past …

Theranostic application of nanoemulsions in chemotherapy

B Gorain, H Choudhury, AB Nair, SK Dubey… - Drug discovery today, 2020 - Elsevier
Highlights•Theranostic nanoemulsions hold possibilities to detect and treat cancer
effectively.•Targeting theranostic approaches received great attention for site-specific …

Current trends in cancer nanotheranostics: metallic, polymeric, and lipid-based systems

CO Silva, JO Pinho, JM Lopes, AJ Almeida, MM Gaspar… - Pharmaceutics, 2019 - mdpi.com
Theranostics has emerged in recent years to provide an efficient and safer alternative in
cancer management. This review presents an updated description of nanotheranostic …