Using conditioned place preference to identify relapse prevention medications
TC Napier, AA Herrold, H De Wit - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Stimuli, including contexts, which predict the availability or onset of a drug effect, can acquire
conditioned incentive motivational properties. These conditioned properties endure after …
conditioned incentive motivational properties. These conditioned properties endure after …
[HTML][HTML] Ghrelin activates the mesolimbic dopamine system via nitric oxide associated mechanisms in the ventral tegmental area
JA Engel, E Pålsson, D Vallöf, E Jerlhag - Nitric Oxide, 2023 - Elsevier
Besides enhanced feeding, the orexigenic peptide ghrelin activates the mesolimbic
dopamine system to cause reward as measured by locomotor stimulation, dopamine release …
dopamine system to cause reward as measured by locomotor stimulation, dopamine release …
Place conditioning in humans: opportunities for translational research
Rationale Translational research, especially research that bridges studies with humans and
nonhuman species, is critical to advancing our understanding of human disorders such as …
nonhuman species, is critical to advancing our understanding of human disorders such as …
Inhibition of neuronal nitric oxide synthase prevents alterations in medial prefrontal cortex excitability induced by repeated cocaine administration
Rationale The medial prefrontal cortex (mPFC), a forebrain region that regulates cognitive
function and reward-motivated behaviors, has been implicated in the neuropathological …
function and reward-motivated behaviors, has been implicated in the neuropathological …
Long-term memory of visually cued fear conditioning: roles of the neuronal nitric oxide synthase gene and cyclic AMP response element-binding protein
JB Kelley, KL Anderson, SL Altmann, Y Itzhak - Neuroscience, 2011 - Elsevier
Nitric oxide (NO) produced by neuronal nitric oxide synthase (nNOS) has a role in late-
phase long-term potentiation (LTP) and long-term memory (LTM) formation. Our recent …
phase long-term potentiation (LTP) and long-term memory (LTM) formation. Our recent …
Involvement of nNOS/NO/sGC/cGMP signaling pathway in cocaine sensitization and in the associated hippocampal alterations: does phosphodiesterase 5 inhibition …
LA Gabach, VP Carlini, MC Monti, LE Maglio… - …, 2013 - Springer
Rationale Repeated cocaine administration induces behavioral sensitization in about 50%
of treated animals. Nitric oxide could be involved in the acquisition and maintenance of …
of treated animals. Nitric oxide could be involved in the acquisition and maintenance of …
Changes in the magnitude of drug‐unconditioned stimulus during conditioning modulate cocaine‐induced place preference in mice
Y Itzhak, KL Anderson - Addiction biology, 2012 - Wiley Online Library
Drug reinforcement learning is relevant for the development of addiction. The present study
investigated how changes in the magnitude of drug‐unconditioned stimulus during …
investigated how changes in the magnitude of drug‐unconditioned stimulus during …
The role of the L-arginine-NO-cGMP-dependent pathway in the development of sensitization to mephedrone effects on the locomotor activity in mice
G Bielecka-Papierz, A Serefko, A Szopa… - Behavioural Brain …, 2023 - Elsevier
Mephedrone, a popular psychostimulating substance widely used illegally in recreational
purposes, exerts in rodents that regularly and intermittently were exposed to it a sensitized …
purposes, exerts in rodents that regularly and intermittently were exposed to it a sensitized …
The efficacy of lidocaine in disrupting cocaine cue-induced memory reconsolidation
Rational Cue-induced craving memories, linked to drug-seeking behaviors, require key
molecular processes for memory reconsolidation. Lidocaine, a sodium channel blocker …
molecular processes for memory reconsolidation. Lidocaine, a sodium channel blocker …
Cardiovascular adjustments during anticipated postural changes
It is well‐documented that feedforward cardiovascular responses occur at the onset of
exercise, but it is unclear if such responses are associated with other types of movements. In …
exercise, but it is unclear if such responses are associated with other types of movements. In …