Recent advances in the treatment of insulin resistance targeting molecular and metabolic pathways: fighting a losing battle?
M Wolosowicz, S Prokopiuk, TW Kaminski - Medicina, 2022 - mdpi.com
Diabetes Mellitus (DM) is amongst the most notable causes of years of life lost worldwide
and its prevalence increases perpetually. The disease is characterized as multisystemic …
and its prevalence increases perpetually. The disease is characterized as multisystemic …
Exercise and metabolic health: the emerging roles of novel exerkines
Physical inactivity is a major cause of chronic diseases. It shortens the health span by
lowering the age of the first chronic disease onset, which leads to decreased quality of life …
lowering the age of the first chronic disease onset, which leads to decreased quality of life …
Normalization of spexin levels in patients with obesity submitted to bariatric surgery
A Bufano, G Iraci Sareri, C Ciuoli, S Cantara… - Obesity Surgery, 2024 - Springer
Purpose Spexin is expressed by white fat tissue and other endocrine organs. A negative
correlation between spexin and gluco-lipidic metabolism, energy homeostasis, and food …
correlation between spexin and gluco-lipidic metabolism, energy homeostasis, and food …
Role of Spexin in White Adipose Tissue Thermogenesis under Basal and Cold-Stimulated Conditions
SE Gambaro, MG Zubiría, AP Giordano… - International Journal of …, 2024 - mdpi.com
Spexin (SPX) is a novel adipokine that plays an emerging role in metabolic diseases due to
its involvement in carbohydrate homeostasis, weight loss, appetite control, and …
its involvement in carbohydrate homeostasis, weight loss, appetite control, and …
Exercise training and spexin ameliorate thyroid changes in obese type 2 diabetic rats: the possible interlaying mechanisms
FH Rizk, RAE Barhoma, MH El-Saka… - American Journal …, 2024 - journals.physiology.org
Thyroid dysfunction and diabetes mellitus are prevalent endocrine disorders that often
coexist and influence each other. The role of spexin (SPX) in diabetes and obesity is well …
coexist and influence each other. The role of spexin (SPX) in diabetes and obesity is well …
Systemic and tissue-specific spexin response to acute treadmill exercise in rats
Abstract Spexin (SPX) is a 14-amino-acid peptide that plays an important role in the
regulation of metabolism and energy homeostasis. It is well known that a variety of bioactive …
regulation of metabolism and energy homeostasis. It is well known that a variety of bioactive …
[HTML][HTML] An update on galanin and spexin and their potential for the treatment of type 2 diabetes and related metabolic disorders
DM Gallagher, FPM O'Harte, N Irwin - Peptides, 2024 - Elsevier
Spexin (SPX) and galanin (GAL) are two neuropeptides widely expressed in the central
nervous system as well as within peripheral tissues in humans and other species. SPX and …
nervous system as well as within peripheral tissues in humans and other species. SPX and …
Cord Blood Spexin Level in Mothers with Obesity—Forecast of Future Obesity?
M Wojciechowska, PA Kolodziejski… - Children, 2023 - mdpi.com
Spexin (SPX) is a peptide that plays an important role in the regulation of food intake and
body weight (BW) by the effect on carbohydrate-lipid metabolism. However, the role of SPX …
body weight (BW) by the effect on carbohydrate-lipid metabolism. However, the role of SPX …
The Investigation of Kisspeptin, Spexin and Galanin in Euthyroid Women with Hashimoto's Thyroiditis
U Can, S Akdu, AH Aktan - Endocrine Research, 2024 - Taylor & Francis
ABSTRACT Objective The hallmarks of Hashimoto's thyroiditis (HT) include the destruction
of thyroid cells by leading to insulin resistance (IR), hypothyroidism, and metabolic …
of thyroid cells by leading to insulin resistance (IR), hypothyroidism, and metabolic …
Liver Protection of Hydroxytyrosol Mediated by Spexin and TRPM2
E Onat, N Kocaman - Journal of Contemporary Medicine, 2023 - dergipark.org.tr
Background/Aim: In the study, the role of Spexin (SPX) and TRPM2 in the protective effect of
Hydroxytyrosol (HT) in rats given Corn Syrup was evaluated. Material and Method: The rats …
Hydroxytyrosol (HT) in rats given Corn Syrup was evaluated. Material and Method: The rats …