Circadian rhythms and disorders of the timing of sleep
The daily alternation between sleep and wakefulness is one of the most dominant features
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …
Circadian rhythm as a therapeutic target
The circadian clock evolved in diverse organisms to integrate external environmental
changes and internal physiology. The clock endows the host with temporal precision and …
changes and internal physiology. The clock endows the host with temporal precision and …
[HTML][HTML] Circadian rhythm disruption and mental health
Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …
Circadian mechanisms in medicine
Circadian Mechanisms in Medicine Molecular insights into diurnal variations in human
physiology and behavior are extending our understanding of a wide range of disease …
physiology and behavior are extending our understanding of a wide range of disease …
Generation of circadian rhythms in the suprachiasmatic nucleus
MH Hastings, ES Maywood… - Nature Reviews …, 2018 - nature.com
The suprachiasmatic nucleus (SCN) of the hypothalamus is remarkable. Despite numbering
only about 10,000 neurons on each side of the third ventricle, the SCN is our principal …
only about 10,000 neurons on each side of the third ventricle, the SCN is our principal …
[HTML][HTML] Rhythms of life: circadian disruption and brain disorders across the lifespan
RW Logan, CA McClung - Nature Reviews Neuroscience, 2019 - nature.com
Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …
hour cycle, and there are strong associations between disrupted circadian rhythms (for …
Multifunctional fiber‐enabled intelligent health agents
The application of wearable devices is promoting the development toward digitization and
intelligence in the field of health. However, the current smart devices centered on human …
intelligence in the field of health. However, the current smart devices centered on human …
Transcriptional architecture of the mammalian circadian clock
JS Takahashi - Nature Reviews Genetics, 2017 - nature.com
Circadian clocks are endogenous oscillators that control 24-hour physiological and
behavioural processes in organisms. These cell-autonomous clocks are composed of a …
behavioural processes in organisms. These cell-autonomous clocks are composed of a …
[HTML][HTML] Genomics of circadian rhythms in health and disease
F Rijo-Ferreira, JS Takahashi - Genome medicine, 2019 - Springer
Circadian clocks are endogenous oscillators that control 24-h physiological and behavioral
processes. The central circadian clock exerts control over myriad aspects of mammalian …
processes. The central circadian clock exerts control over myriad aspects of mammalian …
Circadian rhythm sleep–wake disturbances and depression in young people: implications for prevention and early intervention
JJ Crouse, JS Carpenter, YJC Song, SJ Hockey… - The Lancet …, 2021 - thelancet.com
A rate-limiting step in the prevention and early intervention of depressive disorders in young
people is our insufficient understanding of causal mechanisms. One plausible …
people is our insufficient understanding of causal mechanisms. One plausible …