Helicobacter pylori is responsible for the most commonly found infection in the world's
population. It is the major risk factor for gastric cancer development. Numerous studies …

Gastric cancer is considered to be a type of gastrointestinal tumor and is mostly
accompanied by Helicobacter pylori (HP) infection at the early stage. Hence, the long-term …

Gastric cancer is one of the top causes of cancer-related death globally. Although novel
treatment strategies have been developed, attempts to eradicate gastric cancer have been …

The increasing antibiotic resistance evolved by Helicobacter pylori has alarmingly reduced
the eradication rates of first-line therapies. To overcome the current circulating resistome, we …

Gastric cancer is the fifth most common and fourth type to cause the highest mortality rates
worldwide. The leading cause is related to Helicobacter pylori (H. pylori) infection …

Since the discovery of penicillin in the first half of the last century, antibiotics have become
the pillars of modern medicine for fighting bacterial infections. However, pathogens resistant …

Two-component regulatory systems (TCRS) are ubiquitous signal transduction mechanisms
evolved by bacteria for sensing and adapting to the constant changes that occur in their …

Flavodoxins are small soluble electron transfer proteins widely present in bacteria and
absent in vertebrates. Flavodoxins participate in different metabolic pathways and, in some …

Toxin-antitoxin (TA) systems are small genetic loci composed of two adjacent genes: a toxin
and an antitoxin that prevents toxin action. Despite their wide distribution in bacterial …

Bacterial pathogens employ a general strategy to overcome host defenses by coordinating
the virulence gene expression using dedicated regulatory systems that could raise intricate …