The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review

F Atashi, A Modarressi, MS Pepper - Stem cells and development, 2015 - liebertpub.com
Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …

Effects of oxidative stress on mesenchymal stem cell biology

RA Denu, P Hematti - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Mesenchymal stromal/stem cells (MSCs) are multipotent stem cells present in most fetal and
adult tissues. Ex vivo culture‐expanded MSCs are being investigated for tissue repair and …

Towards a comprehensive theory of obesity and a healthy diet: The causal role of oxidative stress in food addiction and obesity

TO Tobore - Behavioural brain research, 2020 - Elsevier
Background Obesity is a major public health problem whose prevalence has been rapidly
increasing in the United States (US), and globally. It is one of the leading causes of …

The role of bone marrow microenvironment in governing the balance between osteoblastogenesis and adipogenesis

J Li, X Liu, L Zhang - Aging and disease, 2015 - pmc.ncbi.nlm.nih.gov
In the adult bone marrow, osteoblasts and adipocytes share a common precursor called
mesenchymal stem cells (MSCs). The plasticity between the two lineages has been …

Doxorubicin, mesenchymal stem cell toxicity and antitumour activity: implications for clinical use

M Baxter-Holland, CR Dass - Journal of Pharmacy and …, 2018 - academic.oup.com
Objectives The use of doxorubicin, an antineoplastic medication used for the treatment of
cancers via mechanisms that prevent replication of cells or lead to their death, can result in …

[HTML][HTML] Emerging role of Nrf2 in adipocytes and adipose biology

KS Schneider, JY Chan - Advances in Nutrition, 2013 - Elsevier
Maintenance of a balanced redox state within the cell is of critical importance to a wide
variety of biological systems. Nuclear factor erythroid-derived 2-like 2 (Nrf2) is a critical …

Redox modulation of adipocyte differentiation: hypothesis of “Redox Chain” and novel insights into intervention of adipogenesis and obesity

X Wang, C Hai - Free Radical Biology and Medicine, 2015 - Elsevier
In view of the global prevalence of obesity and obesity-associated disorders, it is important
to clearly understand how adipose tissue forms. Accumulating data from various laboratories …

Optimization of oxidative stress for mesenchymal stromal/stem cell engraftment, function and longevity

RA Denu, P Hematti - Free Radical Biology and Medicine, 2021 - Elsevier
Mesenchymal stromal/stem cells (MSCs) are multipotent cells that possess great potential as
a cellular therapeutic based on their ability to differentiate to different lineages and to …

Molecular mechanism of anti‐adipogenic effect of vitexin in differentiating hMSCs

D Gire, J Acharya, S Malik, S Inamdar… - Phytotherapy …, 2021 - Wiley Online Library
In this study, we evaluated a detailed molecular mechanism of anti‐adipogenic activity of
vitexin, apigenin flavone glucoside, present in germinated fenugreek seeds, in differentiating …

Secretome of young mesenchymal stromal cells rejuvenates aged mesenchymal stromal cells by normalizing their phenotype and restoring their differentiation profile

M Das, P Teli, A Vaidya, V Kale - Stem Cells and Development, 2023 - liebertpub.com
During aging, the proliferation and differentiation ability of mesenchymal stem/stromal cells
(MSCs) gets affected, and hence, aged MSCs are not preferred for regenerative purposes …