A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health

M Rodriguez-Concepcion, J Avalos, ML Bonet… - Progress in lipid …, 2018 - Elsevier
Carotenoids are lipophilic isoprenoid compounds synthesized by all photosynthetic
organisms and some non-photosynthetic prokaryotes and fungi. With some notable …

Unraveling plant natural chemical diversity for drug discovery purposes

E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

Targeted knockout of a conserved plant mitochondrial gene by genome editing

J Forner, D Kleinschmidt, EH Meyer, J Gremmels… - Nature Plants, 2023 - nature.com
Fusion proteins derived from transcription activator-like effectors (TALEs) have emerged as
genome editing tools for mitochondria. TALE nucleases (TALENs) have been applied to …

Synthetic biology of plant natural products: From pathway elucidation to engineered biosynthesis in plant cells

X Zhu, X Liu, T Liu, Y Wang, N Ahmed, Z Li… - Plant Communications, 2021 - cell.com
Plant natural products (PNPs) are the main sources of drugs, food additives, and new
biofuels and have become a hotspot in synthetic biology. In the past two decades, the …

Subcellular compartmentalization in the biosynthesis and engineering of plant natural produces

L Yao, X Wu, X Jiang, M Shan, Z Zhang, Y Li… - Biotechnology …, 2023 - Elsevier
Plant natural products (PNPs) are specialized metabolites with diverse bioactivities. They
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …

Exploring uncharted territories of plant specialized metabolism in the postgenomic era

JR Jacobowitz, JK Weng - Annual review of plant biology, 2020 - annualreviews.org
For millennia, humans have used plants for food, raw materials, and medicines, but only
within the past two centuries have we begun to connect particular plant metabolites with …

Plant synthetic biology innovations for biofuels and bioproducts

Y Yang, TA Chaffin, AH Ahkami, E Blumwald… - Trends in …, 2022 - cell.com
Plant-based biosynthesis of fuels, chemicals, and materials promotes environmental
sustainability, which includes decreases in greenhouse gas emissions, water pollution, and …

Targeted introduction of heritable point mutations into the plant mitochondrial genome

J Forner, D Kleinschmidt, EH Meyer, A Fischer… - Nature plants, 2022 - nature.com
The development of technologies for the genetic manipulation of mitochondrial genomes
remains a major challenge. Here we report a method for the targeted introduction of …

Synthetic conversion of leaf chloroplasts into carotenoid-rich plastids reveals mechanistic basis of natural chromoplast development

B Llorente, S Torres-Montilla, L Morelli… - Proceedings of the …, 2020 - National Acad Sciences
Plastids, the defining organelles of plant cells, undergo physiological and morphological
changes to fulfill distinct biological functions. In particular, the differentiation of chloroplasts …

Grafting in plants: recent discoveries and new applications

G Loupit, L Brocard, N Ollat… - Journal of Experimental …, 2023 - academic.oup.com
Grafting is a traditional horticultural technique that makes use of plant wound healing
mechanisms to join two different genotypes together to form one plant. In many agricultural …