Osteoporosis is characterized by low bone mineral density and structural deterioration of
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …

Osteoporosis is a complex human disease that results in increased susceptibility to fragility
fractures. It can be phenotypically characterized using several traits, including bone mineral …

Higher levels of C‐reactive protein (CRP), an inflammatory marker, are associated with
increased fracture risk, although previous studies on CRP and bone mineral density (BMD) …

Context: Diabetes mellitus is associated with increased hip fracture risk, despite being
associated with higher bone mineral density in the femoral neck. Objective: The objective of …

Giant cell tumor is a relatively uncommon but painful tumor of bone, which can metastasize
to the lungs. The RANK pathway is often reported to be involved in the pathogenesis of giant …

The aim of this study was to determine if single‐nucleotide polymorphisms (SNPs) in
RANKL, RANK, and OPG influence bone turnover and bone mineral density (BMD) in men …

To identify the susceptibility genes for osteoporotic fracture in postmenopausal Chinese
women, a two‐stage case‐control association study using joint analysis was conducted in …

Association between 22 single nucleotide polymorphisms (SNPs) in the TNFSF11,
TNFRSF11A, and TNFRSF11B genes in the RANKL/RANK/OPG pathway with bone mineral …

Receptor activator of the nuclear factor-κB ligand (RANKL) and osteoprotegerin genes
(OPG) were identified as susceptible loci for postmenopausal osteoporosis (PMO) in various …

Osteoporosis is an important and complex disorder that is highly prevalent worldwide. This
disease poses a major challenge to modern medicine and its treatment is associated with …