Virus-derived peptides for clinical applications

M Yang, K Sunderland, C Mao - Chemical reviews, 2017 - ACS Publications
Novel affinity agents with high specificity are needed to make progress in disease diagnosis
and therapy. Over the last several years, peptides have been considered to have …

siRNA delivery for treatment of degenerative diseases, new hopes and challenges

F Zahir-Jouzdani, F Mottaghitalab, M Dinarvand… - Journal of Drug Delivery …, 2018 - Elsevier
Degenerative diseases are marked by continuous and progressive deterioration of the
function of cells which is not caused by any underlying trauma or infection. The economic …

DUSP26 induces aortic valve calcification by antagonizing MDM2-mediated ubiquitination of DPP4 in human valvular interstitial cells

Y Wang, D Han, T Zhou, C Chen, H Cao… - European Heart …, 2021 - academic.oup.com
Aims The morbidity and mortality rates of calcific aortic valve disease (CAVD) remain high
while treatment options are limited. Here, we evaluated the role and therapeutic value of …

Enoyl coenzyme a hydratase 1 attenuates aortic valve calcification by suppressing Runx2 via Wnt5a/Ca2+ pathway

C Rao, B Liu, H Qin, Z Du - Journal of Cell Communication and …, 2024 - Wiley Online Library
The morbidity and death rates of calcified aortic valves| calcific aortic valve (CAV) disease
(CAVD) remain high for its limited therapeutic choices. Here, we investigated the function …

MG 53 protein protects aortic valve interstitial cells from membrane injury and fibrocalcific remodeling

TMA Adesanya, M Russell, KH Park… - Journal of the …, 2019 - Am Heart Assoc
Background The aortic valve of the heart experiences constant mechanical stress under
physiological conditions. Maladaptive valve injury responses contribute to the development …

Drug Delivery Systems and Cardiovascular Disease

X Wang, X Liang, J Duan, Y Chen, H Li, K Liu… - … of Biomaterials in the …, 2024 - Springer
Clinically, with the treatment of cardiovascular disease in addition to surgery and
interventional therapy, drug therapy is also a common means. With the development of …

Drug Delivery Systems and Cardiovascular

X Wang, X Liang, J Duan, Y Chen, H Li, K Liu… - Application of Biomaterials … - Springer
The most common form of cardiovascular disease (CVD) is atherosclerosis (AS), which is a
chronic infiammatory process of blood vessel walls caused by changes in cholesterol …

[PDF][PDF] Continuous L-DOPA Secretion by AAV Gene Therapy to Improve the Treatment of Parkinson's Disease

ASLM Antunes - 2016 - kclpure.kcl.ac.uk
Parkinson's disease (PD) is characterised by progressive degeneration of the dopaminergic
neurons in the substantia nigra leading to severe motor complications. Standard oral …

[引用][C] 腺相关病毒载体纯化技术的研究进展

曲伟红 - 中国药房, 2015